Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SLC6A1 [1] Synaptic vesicle cycle D00332 Gabapentin [5] 6, 13, 19, 70, 298
2 SLC6A2 [1] Synaptic vesicle cycle D00228 Amoxapine [1] 46
3 SLC6A2 [1] Synaptic vesicle cycle D04999 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
4 SLC6A2 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
5 SLC6A2 [1] Synaptic vesicle cycle D07448 Amitriptyline [4] 78, 97, 226, 299
6 SLC6A2 [1] Synaptic vesicle cycle D07473 Atomoxetine [4] 6, 8, 13, 17
7 SLC6A2 [1] Synaptic vesicle cycle D07591 Bupropion [5] 8, 18, 21, 96, 171
8 SLC6A2 [1] Synaptic vesicle cycle D07791 Desipramine [2] 120, 156
9 SLC6A2 [1] Synaptic vesicle cycle D07875 Doxepin [1] 6
10 SLC6A2 [1] Synaptic vesicle cycle D07880 Duloxetine [2] 6, 13
11 SLC6A2 [1] Synaptic vesicle cycle D08130 Lisdexamfetamine [1] 13
12 SLC6A2 [1] Synaptic vesicle cycle D08222 Milnacipran [2] 46, 49
13 SLC6A2 [1] Synaptic vesicle cycle D08288 Nortriptyline [2] 6, 226
14 SLC6A2 [1] Synaptic vesicle cycle D08670 Venlafaxine [3] 6, 13, 46
15 SLC6A2 [1] Synaptic vesicle cycle D11688 Ampreloxetine [2] 6, 17
16 SLC6A3 [1] Synaptic vesicle cycle D03215 Armodafinil [3] 6, 13, 84
17 SLC6A3 [1] Synaptic vesicle cycle D04999 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
18 SLC6A3 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
19 SLC6A3 [1] Synaptic vesicle cycle D07591 Bupropion [5] 8, 18, 21, 96, 171
20 SLC6A3 [1] Synaptic vesicle cycle D08130 Lisdexamfetamine [1] 13
21 SLC6A4 [1] Synaptic vesicle cycle D00228 Amoxapine [1] 46
22 SLC6A4 [1] Synaptic vesicle cycle D00326 Fluoxetine [6] 13, 17, 78, 86, 179, 206
23 SLC6A4 [1] Synaptic vesicle cycle D02360 Sertraline [2] 6, 206
24 SLC6A4 [1] Synaptic vesicle cycle D02362 Paroxetine [4] 6, 13, 46, 85
25 SLC6A4 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
26 SLC6A4 [1] Synaptic vesicle cycle D07448 Amitriptyline [4] 78, 97, 226, 299
27 SLC6A4 [1] Synaptic vesicle cycle D07704 Citalopram [7] 6, 8, 13, 18, 46, 98, 127
28 SLC6A4 [1] Synaptic vesicle cycle D07791 Desipramine [2] 120, 156
29 SLC6A4 [1] Synaptic vesicle cycle D07875 Doxepin [1] 6
30 SLC6A4 [1] Synaptic vesicle cycle D07880 Duloxetine [2] 6, 13
31 SLC6A4 [1] Synaptic vesicle cycle D07913 Escitalopram [4] 2, 6, 13, 46
32 SLC6A4 [1] Synaptic vesicle cycle D07945 Fenfluramine [4] 140, 144, 145, 149
33 SLC6A4 [1] Synaptic vesicle cycle D08222 Milnacipran [2] 46, 49
34 SLC6A4 [1] Synaptic vesicle cycle D08288 Nortriptyline [2] 6, 226
35 SLC6A4 [1] Synaptic vesicle cycle D08626 Trazodone [1] 2
36 SLC6A4 [1] Synaptic vesicle cycle D08670 Venlafaxine [3] 6, 13, 46
37 SLC6A4 [1] Synaptic vesicle cycle D10184 Vortioxetine [1] 6
38 SLC6A4 [1] Synaptic vesicle cycle D11688 Ampreloxetine [2] 6, 17
39 SLC18A2 [1] Synaptic vesicle cycle D08575 Tetrabenazine [1] 8
40 SLC18A2 [1] Synaptic vesicle cycle D10675 Valbenazine [1] 8
41 SLC18A2 [1] Synaptic vesicle cycle D10701 Deutetrabenazine [1] 8
42 SNAP25 [1] Synaptic vesicle cycle D00783 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
43 SNAP25 [1] Synaptic vesicle cycle D02735 Botulinum toxin type B [4] 2, 6, 13, 51
44 CACNA1B [2] Synaptic vesicle cycle, Type II diabetes mellitus D01173 Cilnidipine [1] 67