Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
2 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 D02910 💬 Amiodarone [2] 28, 127 💬
4 Alanine, aspartate and glutamate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
5 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
6 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
7 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
8 Aldosterone synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
9 Aldosterone synthesis and secretion 💬
 [1] KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
10 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
11 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
12 Alzheimer disease 💬
 [1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
13 Alzheimer disease 💬
 [1] MAPT 💬 D11384 💬 Hydromethylthionine mesylate [1] 127 💬
14 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
15 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
16 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D02910 💬 Amiodarone [2] 28, 127 💬
17 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
18 Amyotrophic lateral sclerosis 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
19 Amyotrophic lateral sclerosis 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
20 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
21 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
22 beta-Alanine metabolism 💬
 [3] ABAT, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
23 Butanoate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
24 Calcium signaling pathway 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
25 Calcium signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
26 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
27 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
28 Calcium signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬
29 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
30 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
31 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
32 cAMP signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬
33 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 D02910 💬 Amiodarone [2] 28, 127 💬
34 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
35 Cholesterol metabolism 💬
 [1] SORT1 💬 D12427 💬 Latozinemab [2]  2 , 127 💬
36 Cholinergic synapse 💬
 [1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
37 Cholinergic synapse 💬
 [1] ACHE 💬 D04292 💬 Galantamine [2]  6 , 127 💬
38 Cholinergic synapse 💬
 [3] KCNJ12, KCNJ3, KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
39 Circadian entrainment 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
40 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
41 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
42 Circadian entrainment 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
43 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
44 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
45 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
46 Cortisol synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
47 Cushing syndrome 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
48 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
49 Dopaminergic synapse 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
50 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
51 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
52 Dopaminergic synapse 💬
 [3] KCNJ3, KCNJ5, SCN1A 💬 D02910 💬 Amiodarone [2] 28, 127 💬
53 Drug metabolism - other enzymes 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
54 Estrogen signaling pathway 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
55 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
56 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
57 GABAergic synapse 💬
 [3] ABAT, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
58 Gap junction 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
59 Gastric acid secretion 💬
 [1] KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
60 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
61 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
62 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
63 Glutamatergic synapse 💬
 [1] KCNJ3 💬 D02910 💬 Amiodarone [2] 28, 127 💬
64 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
65 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 D04292 💬 Galantamine [2]  6 , 127 💬
66 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
67 GnRH secretion 💬
 [3] KCNJ11, KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
68 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
69 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
70 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
71 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
72 Insulin secretion 💬
 [1] KCNJ11 💬 D02910 💬 Amiodarone [2] 28, 127 💬
73 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
74 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
75 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
76 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
77 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
78 Lysosome 💬
 [1] SORT1 💬 D12427 💬 Latozinemab [2]  2 , 127 💬
79 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
80 MAPK signaling pathway 💬
 [1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
81 MAPK signaling pathway 💬
 [1] MAPT 💬 D11384 💬 Hydromethylthionine mesylate [1] 127 💬
82 Metabolic pathways 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
83 Metabolic pathways 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
84 Morphine addiction 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
85 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
86 Neuroactive ligand-receptor interaction 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
87 Neuroactive ligand-receptor interaction 💬
 [2] CNR1, CNR2 💬 D05099 💬 Nabilone [3]  6 , 13, 127 💬
88 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
89 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
90 Neuroactive ligand-receptor interaction 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬
91 Neurotrophin signaling pathway 💬
 [1] SORT1 💬 D12427 💬 Latozinemab [2]  2 , 127 💬
92 Neutrophil extracellular trap formation 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
93 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
94 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
95 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
96 Oxytocin signaling pathway 💬
 [3] KCNJ12, KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
97 Oxytocin signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬
98 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
99 Pancreatic secretion 💬
 [1] KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
100 Parkinson disease 💬
 [1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
101 Parkinson disease 💬
 [1] MAPT 💬 D11384 💬 Hydromethylthionine mesylate [1] 127 💬
102 Pathways of neurodegeneration - multiple diseases 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
103 Pathways of neurodegeneration - multiple diseases 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
104 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
105 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAPT 💬 D11384 💬 Hydromethylthionine mesylate [1] 127 💬
106 Phagosome 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
107 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
108 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
109 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
110 Propanoate metabolism 💬
 [1] ABAT 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
111 Protein digestion and absorption 💬
 [1] KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
112 Rap1 signaling pathway 💬
 [1] CNR1 💬 D05099 💬 Nabilone [3]  6 , 13, 127 💬
113 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
114 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
115 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
116 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
117 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
118 Renin secretion 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
119 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 D05099 💬 Nabilone [3]  6 , 13, 127 💬
120 Retrograde endocannabinoid signaling 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
121 Salivary secretion 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
122 Serotonergic synapse 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
123 Serotonergic synapse 💬
 [1] SLC6A4 💬 D07704 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
124 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
125 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
126 Spinocerebellar ataxia 💬
 [1] KCND3 💬 D02910 💬 Amiodarone [2] 28, 127 💬
127 Steroid hormone biosynthesis 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
128 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 D07704 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
129 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
130 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
131 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D02910 💬 Amiodarone [2] 28, 127 💬
132 Taurine and hypotaurine metabolism 💬
 [2] GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
133 Thermogenesis 💬
 [1] CNR1 💬 D05099 💬 Nabilone [3]  6 , 13, 127 💬
134 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
135 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
136 Transcriptional misregulation in cancer 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
137 Type I diabetes mellitus 💬
 [2] GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
138 Type II diabetes mellitus 💬
 [1] CACNA1G 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
139 Type II diabetes mellitus 💬
 [1] KCNJ11 💬 D02910 💬 Amiodarone [2] 28, 127 💬
140 Tyrosine metabolism 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
141 Valine, leucine and isoleucine degradation 💬
 [1] ABAT 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
142 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D02910 💬 Amiodarone [2] 28, 127 💬
143 Vibrio cholerae infection 💬
 [1] KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬

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