Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 AMPK signaling pathway 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
2 AMPK signaling pathway 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
3 Bile secretion 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
4 Bile secretion 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
5 Bile secretion 💬
[1] NR1H4 💬 D10699 💬 Cholic Acid [4] 20, 234, 265, 310 💬
6 Estrogen signaling pathway 💬
[1] OPRM1 💬 D07831 💬 Dihydrocodeine [1] 310 💬
7 Metabolic pathways 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
8 Metabolic pathways 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
9 Morphine addiction 💬
[1] OPRM1 💬 D07831 💬 Dihydrocodeine [1] 310 💬
10 Neuroactive ligand-receptor interaction 💬
[1] OPRM1 💬 D07831 💬 Dihydrocodeine [1] 310 💬
11 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
12 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬