Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Epstein-Barr virus infection 💬
[1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Epstein-Barr virus infection 💬
[1] BTK 💬 D10893 💬 Acalabrutinib [2] 46, 61 💬
3 Epstein-Barr virus infection 💬
[1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
4 Epstein-Barr virus infection 💬
[1] BTK 💬 D12467 💬 Evobrutinib [3] 13, 46, 49 💬
5 Epstein-Barr virus infection 💬
[1] BTK 💬 D11457 💬 Fenebrutinib [1] 13 💬
6 Epstein-Barr virus infection 💬
[1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
7 Epstein-Barr virus infection 💬
[1] BTK 💬 D12160 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
8 Epstein-Barr virus infection 💬
[1] BTK 💬 D12285 💬 Remibrutinib [2] 13, 53 💬
9 Epstein-Barr virus infection 💬
[1] BTK 💬 D11422 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
10 Epstein-Barr virus infection 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
11 Epstein-Barr virus infection 💬
[1] CD19 💬 D11757 💬 Inebilizumab [4] 11, 13, 51, 300 💬
12 Epstein-Barr virus infection 💬
[1] CD19 💬 D11496 💬 Obexelimab [1] 300 💬
13 Epstein-Barr virus infection 💬
[3] CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab [1] 46 💬
14 Epstein-Barr virus infection 💬
[3] CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab [2] 96, 97 💬
15 Epstein-Barr virus infection 💬
[1] CD3E 💬 D11463 💬 Mosunetuzumab [1] 49 💬
16 Epstein-Barr virus infection 💬
[1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
17 Epstein-Barr virus infection 💬
[1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
18 Epstein-Barr virus infection 💬
[1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
19 Epstein-Barr virus infection 💬
[1] CD58 💬 D02800 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
20 Epstein-Barr virus infection 💬
[2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
21 Epstein-Barr virus infection 💬
[2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [2] 75, 96 💬
22 Epstein-Barr virus infection 💬
[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
23 Epstein-Barr virus infection 💬
[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
24 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [3] 46, 49, 53 💬
25 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
26 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
27 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
28 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
29 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
30 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
31 Epstein-Barr virus infection 💬
[1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
32 Epstein-Barr virus infection 💬
[1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
33 Epstein-Barr virus infection 💬
[1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
34 Epstein-Barr virus infection 💬
[2] IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
35 Epstein-Barr virus infection 💬
[2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
36 Epstein-Barr virus infection 💬
[1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
37 Epstein-Barr virus infection 💬
[1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
38 Epstein-Barr virus infection 💬
[1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
39 Epstein-Barr virus infection 💬
[1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
40 Epstein-Barr virus infection 💬
[1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
41 Epstein-Barr virus infection 💬
[1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
42 Epstein-Barr virus infection 💬
[1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
43 Epstein-Barr virus infection 💬
[2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
44 Epstein-Barr virus infection 💬
[3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
45 Epstein-Barr virus infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
46 Epstein-Barr virus infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
47 Epstein-Barr virus infection 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
48 Epstein-Barr virus infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
49 Epstein-Barr virus infection 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
50 Epstein-Barr virus infection 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
51 Epstein-Barr virus infection 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
52 Epstein-Barr virus infection 💬
[1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
53 Epstein-Barr virus infection 💬
[1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
54 Epstein-Barr virus infection 💬
[1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
55 Epstein-Barr virus infection 💬
[1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
56 Epstein-Barr virus infection 💬
[1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
57 Epstein-Barr virus infection 💬
[1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
58 Epstein-Barr virus infection 💬
[1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
59 Epstein-Barr virus infection 💬
[1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
60 Epstein-Barr virus infection 💬
[1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
61 Epstein-Barr virus infection 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
62 Epstein-Barr virus infection 💬
[1] TYK2 💬 D11817 💬 Deucravacitinib [3] 49, 96, 97 💬