Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
2 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
3 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
4 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
5 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
6 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
7 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
8 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
9 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
10 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
11 GnRH signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [4] 58, 96, 140, 167 💬
12 GnRH signaling pathway 💬
[1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
13 GnRH signaling pathway 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
14 GnRH signaling pathway 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
15 GnRH signaling pathway 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
16 GnRH signaling pathway 💬
[1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
17 GnRH signaling pathway 💬
[1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
18 GnRH signaling pathway 💬
[1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
19 GnRH signaling pathway 💬
[1] GNRHR 💬 D07665 💬 Cetrorelix [1] 46 💬
20 GnRH signaling pathway 💬
[1] GNRHR 💬 D08027 💬 Gonadorelin [1] 76 💬
21 GnRH signaling pathway 💬
[1] GNRHR 💬 D04405 💬 Goserelin [1]  1  💬
22 GnRH signaling pathway 💬
[1] GNRHR 💬 D02369 💬 Histrelin [1] 76 💬
23 GnRH signaling pathway 💬
[1] GNRHR 💬 D06247 💬 Triptorelin [2] 49, 76 💬
24 GnRH signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
25 GnRH signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
26 GnRH signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
27 GnRH signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
28 GnRH signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
29 GnRH signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
30 GnRH signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
31 GnRH signaling pathway 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
32 GnRH signaling pathway 💬
[1] PRKCD 💬 D09671 💬 Sotrastaurin [1] 97 💬
33 GnRH signaling pathway 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
34 GnRH signaling pathway 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
35 GnRH signaling pathway 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
36 GnRH signaling pathway 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
37 GnRH signaling pathway 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬