Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
3 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
4 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
5 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
6 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
7 Pathogenic Escherichia coli infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
8 Pathogenic Escherichia coli infection 💬
 [1] F2 💬 D09707 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬
9 Pathogenic Escherichia coli infection 💬
 [1] F2 💬 D07144 💬 Dabigatran etexilate [2] 51, 75 💬
10 Pathogenic Escherichia coli infection 💬
 [1] F2 💬 D06410 💬 Thrombomodulin Alfa [1] 85 💬
11 Pathogenic Escherichia coli infection 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
12 Pathogenic Escherichia coli infection 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
13 Pathogenic Escherichia coli infection 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
14 Pathogenic Escherichia coli infection 💬
 [3] IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
15 Pathogenic Escherichia coli infection 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
16 Pathogenic Escherichia coli infection 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
17 Pathogenic Escherichia coli infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
18 Pathogenic Escherichia coli infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
19 Pathogenic Escherichia coli infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
20 Pathogenic Escherichia coli infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
21 Pathogenic Escherichia coli infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
22 Pathogenic Escherichia coli infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
23 Pathogenic Escherichia coli infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
24 Pathogenic Escherichia coli infection 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
25 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [2] 51, 85 💬
26 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
27 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
28 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
29 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
30 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
31 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
32 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
33 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
34 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D11595 💬 Belantamab mafodotin [1] 28 💬
36 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D09587 💬 Brentuximab vedotin [2] 49, 51 💬
37 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
38 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00491 💬 Paclitaxel [2] 46, 85 💬
39 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08675 💬 Vinblastine [2] 34, 65 💬
40 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08679 💬 Vincristine [4] 26, 34, 65, 331 💬