Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Apoptosis 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
2	Apoptosis 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
3	Apoptosis 💬	[1] CTSC 💬	D12120 💬	Brensocatib	[1] 299 💬
4	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
5	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
6	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
7	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
8	Apoptosis 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
9	Apoptosis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
10	Apoptosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
11	Apoptosis 💬	[1] NGF 💬	D09387 💬	Tanezumab	[2] 226, 298 💬
12	Apoptosis 💬	[2] PARP1, PARP2 💬	D09730 💬	Olaparib	[2] 86, 285 💬
13	Apoptosis 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
14	Apoptosis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
15	Apoptosis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
16	Apoptosis 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
17	Apoptosis 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
18	Apoptosis 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
19	Apoptosis 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
20	Apoptosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
21	Apoptosis 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
22	Apoptosis 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
23	Apoptosis 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
24	Apoptosis 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
25	Apoptosis 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
26	Apoptosis 💬	[1] TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
27	Apoptosis 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
28	Apoptosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬