Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 [1] 113 💬 |
2 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
3 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 [2] 46, 61 💬 |
4 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 [3] 46, 49, 53 💬 |
5 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D12467 D12467 💬 |
Evobrutinib | 013 [3] 13, 46, 49 💬 |
6 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 [1] 13 💬 |
7 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 [3] 28, 60, 61 💬 |
8 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 [4] 13, 49, 61, 63 💬 |
9 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D12285 D12285 💬 |
Remibrutinib | 013 [2] 13, 53 💬 |
10 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬 |
11 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [1] 46 💬 |
12 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
FCER1A [1] FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬 |
13 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
FYN [1] FYN 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
14 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
FYN [1] FYN 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
15 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL13 [1] IL13 💬 |
D08857 D08857 💬 |
Anrukinzumab | 097 [1] 97 💬 |
16 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL13 [1] IL13 💬 |
D09633 D09633 💬 |
Lebrikizumab | 085 [1] 85 💬 |
17 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL13 [1] IL13 💬 |
D09979 D09979 💬 |
Tralokinumab | 085 [2] 85, 97 💬 |
18 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
19 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
20 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
21 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
22 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
23 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
24 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
25 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
26 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
27 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
28 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
29 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
30 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
31 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
32 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
33 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
34 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
35 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
36 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
37 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
38 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
39 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
40 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
41 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
42 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
43 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |