Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Malaria 💬
 [5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 Malaria 💬
 [1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
3 Malaria 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
4 Malaria 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
5 Malaria 💬
 [1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
6 Malaria 💬
 [1] IFNG 💬 D11120 💬 Emapalumab [3] 49, 65, 107 💬
7 Malaria 💬
 [1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
8 Malaria 💬
 [1] IL12A 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
9 Malaria 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
10 Malaria 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
11 Malaria 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
12 Malaria 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
13 Malaria 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
14 Malaria 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
15 Malaria 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
16 Malaria 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
17 Malaria 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
18 Malaria 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
19 Malaria 💬
 [1] TLR9 💬 D12275 💬 Cobitolimod [1] 97 💬
20 Malaria 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
21 Malaria 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
22 Malaria 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
23 Malaria 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
24 Malaria 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
25 Malaria 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
26 Malaria 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
27 Malaria 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
28 Malaria 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬