Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Hepatitis C 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Hepatitis C 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
3 Hepatitis C 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
4 Hepatitis C 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
5 Hepatitis C 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
6 Hepatitis C 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
7 Hepatitis C 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
8 Hepatitis C 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
9 Hepatitis C 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
10 Hepatitis C 💬
 [1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
11 Hepatitis C 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
12 Hepatitis C 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
13 Hepatitis C 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
14 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [3] 46, 49, 53 💬
15 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
16 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
17 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
18 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
19 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
20 Hepatitis C 💬
 [2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
21 Hepatitis C 💬
 [1] IFNG 💬 D11120 💬 Emapalumab [3] 49, 65, 107 💬
22 Hepatitis C 💬
 [1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
23 Hepatitis C 💬
 [1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
24 Hepatitis C 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
25 Hepatitis C 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
26 Hepatitis C 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
27 Hepatitis C 💬
 [1] JAK1 💬 D10653 💬 Peficitinib [1] 46 💬
28 Hepatitis C 💬
 [1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
29 Hepatitis C 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
30 Hepatitis C 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
31 Hepatitis C 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
32 Hepatitis C 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
33 Hepatitis C 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
34 Hepatitis C 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
35 Hepatitis C 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
36 Hepatitis C 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
37 Hepatitis C 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
38 Hepatitis C 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
39 Hepatitis C 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
40 Hepatitis C 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
41 Hepatitis C 💬
 [1] PPARA 💬 D11208 💬 Elafibranor [2] 93, 94 💬
42 Hepatitis C 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
43 Hepatitis C 💬
 [1] PPARA 💬 D10711 💬 Pemafibrate [1] 93 💬
44 Hepatitis C 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
45 Hepatitis C 💬
 [1] RXRA 💬 D02754 💬 Acitretin [1] 37 💬
46 Hepatitis C 💬
 [1] RXRA 💬 D02815 💬 Alitretinoin [1] 49 💬
47 Hepatitis C 💬
 [1] RXRA 💬 D03106 💬 Bexarotene [2] 13, 75 💬
48 Hepatitis C 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
49 Hepatitis C 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
50 Hepatitis C 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
51 Hepatitis C 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
52 Hepatitis C 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
53 Hepatitis C 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
54 Hepatitis C 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
55 Hepatitis C 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
56 Hepatitis C 💬
 [1] TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
57 Hepatitis C 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
58 Hepatitis C 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
59 Hepatitis C 💬
 [1] TYK2 💬 D11817 💬 Deucravacitinib [3] 49, 96, 97 💬