Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Allograft rejection 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
2	Allograft rejection 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
3	Allograft rejection 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
4	Allograft rejection 💬	[1] CD40LG 💬	D06193 💬	Toralizumab	[1] 63 💬
5	Allograft rejection 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6	Allograft rejection 💬	[2] CD80, CD86 💬	D03222 💬	Belatacept	[1] 46 💬
7	Allograft rejection 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
8	Allograft rejection 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
9	Allograft rejection 💬	[2] IL10, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
10	Allograft rejection 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
11	Allograft rejection 💬	[1] IL4 💬	D03117 💬	Binetrakin	[1] 46 💬
12	Allograft rejection 💬	[1] IL5 💬	D04923 💬	Mepolizumab	[4] 44, 45, 98, 162 💬
13	Allograft rejection 💬	[1] IL5 💬	D08985 💬	Reslizumab	[2] 44, 98 💬
14	Allograft rejection 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
15	Allograft rejection 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
16	Allograft rejection 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
17	Allograft rejection 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
18	Allograft rejection 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
19	Allograft rejection 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
20	Allograft rejection 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
21	Allograft rejection 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
22	Allograft rejection 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
23	Allograft rejection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬