Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
4 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
5 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
6 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
7 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
11 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
12 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
13 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
14 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
15 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
16 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
17 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
18 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
19 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
20 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
21 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
22 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
23 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
24 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
25 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
26 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
27 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
28 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
29 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
30 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
31 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
32 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
33 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
34 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
35 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
36 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
37 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
38 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
39 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
40 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
41 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
42 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
43 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
44 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
45 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
46 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
47 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
48 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
49 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
50 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
51 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
52 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
53 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
54 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
55 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
56 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
57 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
58 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
59 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
60 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
61 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
62 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
63 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
64 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
65 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
66 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
67 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
68 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
69 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
70 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
71 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
72 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
73 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
74 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
75 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
76 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
77 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
78 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
79 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
80 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
81 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
82 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
83 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
84 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
85 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
86 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
87 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
88 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
89 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
90 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
91 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
92 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
93 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
94 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
95 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
96 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
97 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
98 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
99 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
100 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
101 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
102 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
103 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
104 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
105 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
106 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
107 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
108 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
109 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
110 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
111 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
112 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
113 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
114 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
115 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
116 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
117 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
118 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
119 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
120 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
121 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
122 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
123 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
124 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
125 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
126 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
127 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
128 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
129 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL1A [1] IL1A 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
130 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
131 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
132 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
133 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
134 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
135 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
136 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
137 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
138 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
139 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
140 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
141 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
142 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
143 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
144 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
145 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
146 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
147 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
148 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
149 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
150 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
151 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
152 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
153 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [2] JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
154 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
155 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
156 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
157 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
158 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
159 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
160 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 047 [12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
161 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
162 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
163 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
164 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
165 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
166 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
167 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
168 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
169 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
170 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
171 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
172 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
173 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
174 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
175 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
176 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
177 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
178 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
179 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
180 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
181 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
182 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
183 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
184 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
185 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
186 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
187 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
188 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
189 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
190 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
191 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
192 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
193 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
194 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
195 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
196 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
197 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
198 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
199 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
200 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
201 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
202 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
203 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
204 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
205 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
206 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
207 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
208 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
209 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
210 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
211 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
212 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
213 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
214 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
215 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
216 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
217 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
218 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
219 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
220 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
221 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
222 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
223 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
224 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
225 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
226 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
227 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
228 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
229 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
230 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
231 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
232 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
233 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
234 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
235 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
236 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
237 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
238 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
239 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
240 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
241 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
242 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
243 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
244 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
245 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
246 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
247 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
248 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
249 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
250 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
251 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
252 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
253 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
254 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
255 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
256 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
257 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
258 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
259 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
260 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
261 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
262 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
263 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
264 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
265 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
266 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
267 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
268 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
269 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
270 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
271 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
272 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
273 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
274 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
275 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
276 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
277 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
278 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
279 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
280 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
281 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
282 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
283 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
284 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
285 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
286 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
287 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
288 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
289 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
290 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
291 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
292 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
293 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
294 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
295 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
296 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
297 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
298 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
299 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
300 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
301 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
302 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
303 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
304 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
305 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
306 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
307 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
308 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
309 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
310 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
311 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
312 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
313 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
314 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
315 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
316 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
317 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
318 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
319 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
320 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
321 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
322 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
323 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
324 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
325 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
326 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
327 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
328 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
329 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
330 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
331 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
332 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
333 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
334 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
335 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
336 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
337 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
338 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
339 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
340 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
341 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
342 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
343 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
344 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
345 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
346 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
347 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
348 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
349 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
350 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
351 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
352 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
353 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
354 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
355 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
356 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
357 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
358 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
359 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
360 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
361 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
362 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
363 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
364 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
365 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
366 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
367 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
368 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
369 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
370 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
371 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
372 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
373 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
374 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
375 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
376 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
377 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
378 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
379 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
380 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
381 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
382 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
383 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
384 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
385 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
386 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
387 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
388 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
389 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
390 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
391 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
392 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
393 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
394 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
395 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
396 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
397 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
398 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
399 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
400 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
401 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
402 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
403 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
404 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
405 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
406 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
407 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
408 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
409 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
410 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
411 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
412 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
413 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
414 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
415 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
416 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
417 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
418 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
419 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
420 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
421 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
422 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
423 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
424 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
425 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
426 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
427 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
428 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
429 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
430 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
431 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
432 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
433 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
434 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
435 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
436 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
437 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
438 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
439 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
440 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
441 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
442 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
443 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
444 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
445 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
446 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
447 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
448 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
449 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
450 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
451 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
452 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
453 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
454 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
455 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
456 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
457 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
458 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
459 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
460 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
461 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
462 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
463 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
464 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
465 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
466 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
467 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
468 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
469 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
470 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
471 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
472 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
473 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
474 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
475 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
476 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
477 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
478 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
479 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
480 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
481 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
482 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
483 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
484 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
485 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
486 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
487 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
488 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
489 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
490 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
491 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
492 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
493 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
494 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
495 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
496 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
497 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
498 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
499 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
500 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
501 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
502 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
503 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
504 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
505 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
506 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
507 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
508 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
509 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
510 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
511 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
512 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
513 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
514 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
515 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
516 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
517 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
518 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
519 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
520 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
521 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
522 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
523 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
524 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
525 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
526 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
527 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
528 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
529 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
530 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
531 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
532 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
533 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
534 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
535 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
536 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
537 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
538 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
539 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00385 D00385 💬 |
Triamcinolone | 035 [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
540 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00983 D00983 💬 |
Triamcinolone | 035 [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
541 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00984 D00984 💬 |
Triamcinolone | 035 [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
542 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00985 D00985 💬 |
Triamcinolone | 035 [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
543 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D06216 D06216 💬 |
Triamcinolone | 035 [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
544 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
545 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
546 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
547 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
548 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
549 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
550 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
551 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
552 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
553 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
554 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
555 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
556 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
557 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
558 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
559 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
560 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
561 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
562 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
563 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
564 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
565 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
566 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
567 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
568 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
569 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
570 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
571 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
572 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
573 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
574 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
575 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
576 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
577 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
JAK3 [1] JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
578 | One carbon pool by folate 💬 Related to 3 target genes, 3 drugs (DrugBank) and 39 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
579 | One carbon pool by folate 💬 Related to 3 target genes, 3 drugs (DrugBank) and 39 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
580 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
581 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
582 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
583 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
584 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
585 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
586 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
587 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
588 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
589 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
590 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
591 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
592 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
593 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
594 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
595 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
596 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
597 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
598 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
599 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
600 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
601 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
602 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
603 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
604 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
605 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
606 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
607 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
608 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
609 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
610 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
611 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
612 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
613 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
614 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
615 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
616 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
617 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
618 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
619 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
620 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
621 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
622 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
623 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
624 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
625 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
626 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
627 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
628 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
629 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
630 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
631 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
632 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
633 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
634 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
635 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
636 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
637 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
638 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
639 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
640 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
641 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
642 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
643 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
644 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
645 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
646 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
647 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
648 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
649 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
650 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
651 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
652 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
653 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
654 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
655 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
656 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
657 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
658 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
659 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
660 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
661 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
662 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
663 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
664 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
665 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
666 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
667 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
668 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
669 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
670 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
671 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
672 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
673 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
674 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
675 | Primary immunodeficiency 💬 Related to 11 target genes, 21 drugs (DrugBank) and 27 diseases in DDrare |
JAK3 [1] JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
676 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
677 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
678 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
679 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
680 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
681 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
682 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
683 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
684 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
685 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
686 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
687 | Proteasome 💬 Related to 2 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
688 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
689 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
690 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
691 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
692 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
693 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
694 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
695 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
696 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
697 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
698 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
699 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
700 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
701 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
702 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
703 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
704 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
705 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
706 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
707 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
708 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
709 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
710 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
711 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
712 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
713 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
714 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
715 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
716 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
717 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
718 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
719 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
720 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
721 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
722 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
723 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
724 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
725 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
726 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
727 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
728 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
729 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
730 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
731 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
732 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
733 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00456 D00456 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
734 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00678 D00678 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
735 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
736 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
737 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
738 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
739 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
740 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
741 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
742 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
743 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
744 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
745 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
746 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
747 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
748 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
749 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 20 target genes, 25 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
750 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 20 target genes, 25 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
751 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 20 target genes, 25 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
752 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
753 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
754 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
755 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
756 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
757 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
758 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
759 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
760 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
761 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
762 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
763 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
764 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
765 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
766 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
767 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
768 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
769 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
770 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
771 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
772 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
773 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
774 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
775 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
776 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
777 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00456 D00456 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
778 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00678 D00678 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
779 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
780 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
781 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
782 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
783 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
784 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
785 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
786 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
787 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
788 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
789 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
790 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
791 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
792 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
793 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
794 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
795 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
796 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
797 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
798 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
799 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
800 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
801 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
802 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
803 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
804 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
805 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
806 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
807 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
808 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
809 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
810 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
811 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
812 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
813 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
814 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
815 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
816 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
817 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
818 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
819 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
820 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
821 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
822 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
823 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
824 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
825 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
826 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
827 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
828 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
829 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
830 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
831 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
832 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
833 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
834 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
835 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
836 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
837 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
838 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
839 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
840 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
841 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
842 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
843 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
844 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
845 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
846 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
847 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
848 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
849 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
850 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
851 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
852 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
853 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
854 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
855 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
856 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
857 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
858 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
859 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
860 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
861 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
862 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
863 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
864 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
865 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
866 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
867 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
868 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
869 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
870 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
871 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
872 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
873 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
874 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
875 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
876 | Viral carcinogenesis 💬 Related to 31 target genes, 22 drugs (DrugBank) and 43 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
877 | Viral carcinogenesis 💬 Related to 31 target genes, 22 drugs (DrugBank) and 43 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
878 | Viral carcinogenesis 💬 Related to 31 target genes, 22 drugs (DrugBank) and 43 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
879 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
880 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
881 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
882 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
883 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
884 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
885 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
886 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
887 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
888 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
889 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
890 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
891 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
892 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
893 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
894 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
895 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |