Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
ABCC8 [1] ABCC8 💬 |
D00294 D00294 💬 |
Diazoxide | 013 [2] 13, 193 💬 |
2 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
ABCC8 [1] ABCC8 💬 |
D00418 D00418 💬 |
Minoxidil | 179 [1] 179 💬 |
3 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
ABCC8 [1] ABCC8 💬 |
D00594 D00594 💬 |
Repaglinide | 006 [3] 6 , 21, 299 💬 |
4 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
ABCD1 [1] ABCD1 💬 |
D12150 D12150 💬 |
Elivaldogene autotemcel | 020 [1] 20 💬 |
5 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
6 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
7 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
8 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
9 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
10 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
11 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
12 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
BRAF [4] BRAF, FLT3, KIT, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
13 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
BRAF [4] BRAF, FLT3, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
14 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
15 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
16 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
FLT3 [2] FLT3, KIT 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
17 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
FLT3 [2] FLT3, KIT 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
18 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
19 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
20 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
21 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
22 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
23 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
24 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
25 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
26 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
27 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
28 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [3] 2 , 17, 127 💬 |
29 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
30 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
31 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
32 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
33 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
34 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
35 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
PML [2] PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
36 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
37 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
38 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 [1] 299 💬 |
39 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
40 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
41 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA [1] RARA 💬 |
D06543 D06543 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 |
42 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
43 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
44 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
45 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
46 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
47 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
48 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
49 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
50 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
51 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
FGFR1 [1] FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
52 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
FGFR1 [1] FGFR1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
53 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
FYN [3] FYN, SRC, YES1 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
54 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
FYN [3] FYN, SRC, YES1 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
55 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
56 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
57 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
58 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
59 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
60 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
61 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
62 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
63 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
64 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
65 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
66 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
67 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
68 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
69 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
70 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
71 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
72 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
LEPR [1] LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 [1] 265 💬 |
73 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
74 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
75 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
76 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
77 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
78 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [1] 93 💬 |
79 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [5] 8 , 79, 93, 94, 265 💬 |
80 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
81 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
82 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
83 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PRKCQ [1] PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
84 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
85 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
86 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
87 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
88 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
89 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
90 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
91 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
92 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
93 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
94 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
95 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
96 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
97 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
98 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
99 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 [1] 13 💬 |
100 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
101 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
102 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00608 D00608 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
103 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
104 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 [2] 6 , 206 💬 |
105 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 [1] 85 💬 |
106 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
107 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
108 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
109 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
110 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
111 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
112 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 [1] 22 💬 |
113 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
114 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00610 D00610 💬 |
Terazosin | 006 [1] 6 💬 |
115 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
116 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
117 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
118 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
119 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
120 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
121 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
122 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
123 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
124 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
125 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
126 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
127 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
128 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
129 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
130 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
131 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
132 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
133 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
134 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
135 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
136 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
137 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
138 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
139 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
140 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
141 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
142 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
143 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
144 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
145 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
146 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
147 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
148 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
149 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
150 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
151 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
152 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
153 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
154 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
155 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
156 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
157 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
158 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
159 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
160 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
161 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
162 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
163 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
164 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
165 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
166 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
167 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
168 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
169 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
170 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
171 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
172 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
173 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [2] AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
174 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [2] AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
175 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
176 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
177 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
178 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
179 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
180 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
181 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
182 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
183 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
184 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
185 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
186 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
187 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
188 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
189 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
190 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
191 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
192 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
193 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
194 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
195 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
196 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
D11203 D11203 💬 |
Mirogabalin | 070 [1] 70 💬 |
197 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
198 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
199 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
200 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
201 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
202 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
203 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D01450 D01450 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
204 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
205 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00252 D00252 💬 |
Carbamazepine | 013 [2] 13, 231 💬 |
206 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D03492 D03492 💬 |
Cibenzoline | 058 [1] 58 💬 |
207 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D11155 D11155 💬 |
Eleclazine | 058 [1] 58 💬 |
208 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00638 D00638 💬 |
Flecainide | 006 [1] 6 💬 |
209 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D07962 D07962 💬 |
Flecainide | 006 [1] 6 💬 |
210 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00354 D00354 💬 |
Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬 |
211 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D01287 D01287 💬 |
Levobupivacaine | 046 [1] 46 💬 |
212 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08116 D08116 💬 |
Levobupivacaine | 046 [1] 46 💬 |
213 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
214 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
215 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
216 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
217 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
218 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00533 D00533 💬 |
Oxcarbazepine | 013 [1] 13 💬 |
219 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D01768 D01768 💬 |
Oxybuprocaine | 006 [1] 6 💬 |
220 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08319 D08319 💬 |
Oxybuprocaine | 006 [1] 6 💬 |
221 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00512 D00512 💬 |
Phenytoin | 013 [1] 13 💬 |
222 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D02103 D02103 💬 |
Phenytoin | 013 [1] 13 💬 |
223 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00642 D00642 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
224 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00643 D00643 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
225 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D02272 D02272 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
226 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08458 D08458 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
227 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D04048 D04048 💬 |
Ropivacaine | 036 [3] 36, 46, 70 💬 |
228 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D08490 D08490 💬 |
Ropivacaine | 036 [3] 36, 46, 70 💬 |
229 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D05775 D05775 💬 |
Rufinamide | 144 [1] 144 💬 |
230 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
231 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
232 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
233 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
234 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
235 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
236 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
237 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
238 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
239 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
240 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
241 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
242 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
243 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
244 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
245 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
246 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
247 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
248 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
249 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
250 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
251 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
252 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
253 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
254 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
255 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
256 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
257 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
258 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
259 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
260 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
261 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
262 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
263 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
CDK4 [1] CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
264 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
265 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
266 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
267 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
268 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
269 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
270 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
271 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
272 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
273 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
274 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
275 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
276 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
277 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
278 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
279 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
280 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
PRKCD [2] PRKCD, PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
281 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
282 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
283 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
284 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
285 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
286 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
287 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
288 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
289 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
290 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
291 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
292 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
293 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
294 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
VEGFA [2] VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
295 | Alanine, aspartate and glutamate metabolism 💬 Related to 5 target genes, 3 drugs (DrugBank) and 22 diseases in DDrare |
ABAT [1] ABAT 💬 |
D00535 D00535 💬 |
Vigabatrin | 145 [2] 145, 158 💬 |
296 | Alanine, aspartate and glutamate metabolism 💬 Related to 5 target genes, 3 drugs (DrugBank) and 22 diseases in DDrare |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
297 | Alanine, aspartate and glutamate metabolism 💬 Related to 5 target genes, 3 drugs (DrugBank) and 22 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
298 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
299 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [3] 2 , 62, 222 💬 |
300 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 [2] 62, 109 💬 |
301 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
302 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 |
303 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D11477 D11477 💬 |
Pozelimab | 011 [2] 11, 62 💬 |
304 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 |
305 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 [1] C5 💬 |
D11838 D11838 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 |
306 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 |
307 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
308 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
309 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
310 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
311 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
312 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D11550 D11550 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 |
313 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
314 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
315 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A [1] IL17A 💬 |
D11127 D11127 💬 |
Tibulizumab | 053 [1] 53 💬 |
316 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17RA [1] IL17RA 💬 |
D10061 D10061 💬 |
Brodalumab | 037 [2] 37, 51 💬 |
317 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
318 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
319 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
320 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
321 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
322 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
323 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
324 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
325 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
326 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
327 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
328 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
329 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [1] 93 💬 |
330 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [5] 8 , 79, 93, 94, 265 💬 |
331 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
332 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
333 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
334 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
335 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
336 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
337 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
338 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
339 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
340 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
341 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
342 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
343 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
344 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
345 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
346 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 [1] 6 💬 |
347 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 [1] 6 💬 |
348 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
349 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
350 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 [1] 6 💬 |
351 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
352 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
353 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
354 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
355 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
356 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
357 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
358 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
359 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
360 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
361 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
362 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
363 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
364 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
365 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
366 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
367 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
368 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
369 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
370 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
371 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
372 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
373 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
374 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
375 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
376 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
377 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
378 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00702 D00702 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
379 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07593 D07593 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
380 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
381 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
382 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
383 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
384 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
385 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
386 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
387 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
388 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 [1] 8 💬 |
389 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01898 D01898 💬 |
Haloperidol | 008 [1] 8 💬 |
390 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
391 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
392 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 [1] 6 💬 |
393 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 051 [1] 51 💬 |
394 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D02213 D02213 💬 |
Metoclopramide | 051 [1] 51 💬 |
395 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05008 D05008 💬 |
Metoclopramide | 051 [1] 51 💬 |
396 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
397 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
398 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
399 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
400 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 [1] 6 💬 |
401 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
402 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
403 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
404 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00458 D00458 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
405 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
406 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
407 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
408 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
409 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 [2] 6 , 127 💬 |
410 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
411 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
412 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
413 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 [1] 8 💬 |
414 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00799 D00799 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
415 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
416 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
417 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
418 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
419 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
420 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
421 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
422 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
423 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
424 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
425 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
426 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
427 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
428 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
429 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
430 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
431 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
432 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
433 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
434 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
435 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
436 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
437 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
438 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
439 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
440 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
441 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
442 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
443 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
444 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
445 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
446 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
447 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
448 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10701 D10701 💬 |
Deutetrabenazine | 008 [1] 8 💬 |
449 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D08575 D08575 💬 |
Tetrabenazine | 008 [1] 8 💬 |
450 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10675 D10675 💬 |
Valbenazine | 008 [1] 8 💬 |
451 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D03215 D03215 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 |
452 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
453 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
454 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
455 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D08130 D08130 💬 |
Lisdexamfetamine | 013 [1] 13 💬 |
456 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D01296 D01296 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
457 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
458 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
459 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
460 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
461 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
462 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
463 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
464 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
465 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
466 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
467 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
468 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
469 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
470 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
471 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
472 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
473 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
474 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
475 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
476 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
477 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
478 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
479 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
480 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
481 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
482 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
483 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
484 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
485 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
486 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
487 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
488 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
489 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
490 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
491 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
492 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
493 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CYP11B2 [1] CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 [1] 75 💬 |
494 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
KCNJ5 [1] KCNJ5 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
495 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
KCNJ5 [1] KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
496 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [15] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 |
497 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00284 D00284 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 |
498 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
499 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
500 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
501 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
502 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
503 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
504 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
505 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
506 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
507 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
508 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
509 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
510 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
511 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
512 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
513 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
514 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
515 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
516 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
517 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
518 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
519 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D10528 D10528 💬 |
Aldosterone | 222 [1] 222 💬 |
520 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D01115 D01115 💬 |
Eplerenone | 075 [4] 75, 113, 210, 215 💬 |
521 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D00986 D00986 💬 |
Fludrocortisone | 006 [3] 6 , 17, 81 💬 |
522 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D07967 D07967 💬 |
Fludrocortisone | 006 [3] 6 , 17, 81 💬 |
523 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D00443 D00443 💬 |
Spironolactone | 058 [7] 58, 67, 86, 113, 210, 218, 225 💬 |
524 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
525 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
526 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
SCNN1A [3] SCNN1A, SCNN1B, SCNN1G 💬 |
D00649 D00649 💬 |
Amiloride | 013 [4] 13, 67, 225, 299 💬 |
527 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
SCNN1A [3] SCNN1A, SCNN1B, SCNN1G 💬 |
D07447 D07447 💬 |
Amiloride | 013 [4] 13, 67, 225, 299 💬 |
528 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
529 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
530 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
531 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
532 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
533 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
534 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
535 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
536 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
537 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
538 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
539 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
540 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
541 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
542 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
543 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
544 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
545 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
546 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
547 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
548 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
549 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
550 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
551 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
552 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
ADAM17 [1] ADAM17 💬 |
D08859 D08859 💬 |
Apratastat | 046 [1] 46 💬 |
553 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
APH1A [4] APH1A, NCSTN, PSEN1, PSENEN 💬 |
D09010 D09010 💬 |
Tarenflurbil | 013 [1] 13 💬 |
554 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
555 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
556 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
557 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
558 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
559 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
560 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
561 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
562 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
563 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
564 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
565 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
566 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
567 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
568 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
569 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
570 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
571 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
572 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
573 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
574 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
575 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
576 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
577 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [2] 2 , 299 💬 |
578 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [2] 2 , 299 💬 |
579 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [2] 2 , 299 💬 |
580 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [2] 2 , 299 💬 |
581 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D01000 D01000 💬 |
Bethanechol | 098 [1] 98 💬 |
582 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
583 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
584 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
585 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
586 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
587 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
588 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
589 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
590 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00481 D00481 💬 |
Propantheline | 026 [1] 26 💬 |
591 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
592 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
593 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
594 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [3] 6 , 13, 19 💬 |
595 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM3, CHRM5, CHRNA7 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
596 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00661 D00661 💬 |
Cevimeline | 053 [1] 53 💬 |
597 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
598 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01699 D01699 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
599 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
600 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
601 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
602 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
603 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
604 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01269 D01269 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
605 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
606 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
607 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01148 D01148 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
608 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D03365 D03365 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
609 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D05156 D05156 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
610 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D05157 D05157 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
611 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
612 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
613 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
614 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
615 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
616 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
617 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
618 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
619 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
620 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
621 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
622 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
623 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
624 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
625 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
626 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
627 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
628 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
629 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
630 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
631 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
632 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
633 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
634 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
635 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
636 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
637 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
638 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
639 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
640 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
641 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
642 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
643 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
644 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAPT [1] MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 [3] 5 , 7 , 127 💬 |
645 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAPT [1] MAPT 💬 |
D11293 D11293 💬 |
Gosuranemab | 005 [1] 5 💬 |
646 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [1] 58 💬 |
647 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
648 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
649 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
650 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
651 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
652 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
653 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
654 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
655 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
656 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
657 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
658 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
659 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D08880 D08880 💬 |
Carfilzomib | 028 [1] 28 💬 |
660 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D10130 D10130 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 |
661 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
662 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
663 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
664 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
665 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
666 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
667 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
668 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
669 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
670 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
671 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
672 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
673 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
674 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
675 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
676 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
677 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
678 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
679 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
680 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
681 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
682 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
683 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
684 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
685 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
686 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
687 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
688 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
689 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
690 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
691 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
692 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
693 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
694 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
695 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
696 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
RTN4 [1] RTN4 💬 |
D10331 D10331 💬 |
Ozanezumab | 002 [1] 2 💬 |
697 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
SNCA [1] SNCA 💬 |
D11420 D11420 💬 |
Prasinezumab | 006 [1] 6 💬 |
698 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
699 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
700 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
701 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
702 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
703 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
704 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
705 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
706 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
707 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 [1] 28 💬 |
708 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D09587 D09587 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 |
709 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
710 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00491 D00491 💬 |
Paclitaxel | 046 [2] 46, 85 💬 |
711 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D05333 D05333 💬 |
Paclitaxel | 046 [2] 46, 85 💬 |
712 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D01068 D01068 💬 |
Vinblastine | 034 [2] 34, 65 💬 |
713 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 [2] 34, 65 💬 |
714 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D02197 D02197 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 |
715 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 |
716 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
717 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
718 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
719 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
720 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
721 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
722 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
723 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
724 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
725 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
726 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
727 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
728 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
729 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
730 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
731 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
732 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
733 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
734 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
735 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
736 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
737 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
738 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
739 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
740 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
741 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
742 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
743 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
744 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
745 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
746 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
747 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
748 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
749 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
750 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
751 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
752 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
753 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
754 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
755 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
756 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
757 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
758 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
759 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
760 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
761 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
762 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
763 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
764 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
765 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
766 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
767 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
768 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
769 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
770 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
771 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
772 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
773 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
774 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
775 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
776 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
777 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
778 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
779 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
780 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
781 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
782 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
783 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
784 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
785 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
786 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
787 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
788 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
789 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
790 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
791 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
792 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
793 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
794 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
795 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
796 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
797 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
798 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
799 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
800 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
801 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
802 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
803 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
804 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
805 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
806 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
807 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10701 D10701 💬 |
Deutetrabenazine | 008 [1] 8 💬 |
808 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D08575 D08575 💬 |
Tetrabenazine | 008 [1] 8 💬 |
809 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10675 D10675 💬 |
Valbenazine | 008 [1] 8 💬 |
810 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D03215 D03215 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 |
811 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
812 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
813 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
814 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D08130 D08130 💬 |
Lisdexamfetamine | 013 [1] 13 💬 |
815 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D01296 D01296 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
816 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
817 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 [1] 13 💬 |
818 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
819 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
820 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
821 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
822 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
823 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
824 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00608 D00608 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
825 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
826 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
827 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
828 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
829 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
830 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
831 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 [2] 6 , 206 💬 |
832 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 [1] 85 💬 |
833 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
834 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
835 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
836 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
837 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
838 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
839 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
840 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
841 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 [1] 22 💬 |
842 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
843 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
844 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
845 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
846 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
847 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
848 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D00610 D00610 💬 |
Terazosin | 006 [1] 6 💬 |
849 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
850 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
851 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
852 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
853 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
854 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
855 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
856 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
857 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
858 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
859 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
860 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00892 D00892 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
861 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
862 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
863 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
864 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
865 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
866 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
867 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
868 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
869 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
870 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
871 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
872 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
873 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
874 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
875 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
876 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
LEPR [1] LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 [1] 265 💬 |
877 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
878 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
879 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
880 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
881 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
882 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
883 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
884 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
885 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
886 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
887 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
888 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
889 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
890 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
891 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
892 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIA1 [2] GRIA1, GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
893 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIA1 [2] GRIA1, GRIA2 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
894 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIA1 [2] GRIA1, GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
895 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
896 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
897 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
898 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
899 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
900 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
901 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
902 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
903 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
904 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
905 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
906 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
907 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
908 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
909 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
HDAC6 [1] HDAC6 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
910 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
911 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
912 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
913 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
914 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
915 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
916 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
917 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
918 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
919 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
920 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
921 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
922 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D08880 D08880 💬 |
Carfilzomib | 028 [1] 28 💬 |
923 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D10130 D10130 💬 |
Ixazomib | 013 [5] 13, 16, 28, 51, 61 💬 |
924 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
SIGMAR1 [1] SIGMAR1 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
925 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
SOD1 [1] SOD1 💬 |
D11811 D11811 💬 |
Tofersen | 002 [1] 2 💬 |
926 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
927 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
928 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
929 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
930 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
931 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
932 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
933 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
934 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
935 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
936 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
937 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 [1] 28 💬 |
938 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D09587 D09587 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 |
939 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
940 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00491 D00491 💬 |
Paclitaxel | 046 [2] 46, 85 💬 |
941 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D05333 D05333 💬 |
Paclitaxel | 046 [2] 46, 85 💬 |
942 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D01068 D01068 💬 |
Vinblastine | 034 [2] 34, 65 💬 |
943 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 [2] 34, 65 💬 |
944 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D02197 D02197 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 |
945 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 |
946 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
947 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
948 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
949 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
950 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
951 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
952 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
953 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
954 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
955 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
956 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
957 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
958 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
959 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
960 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
961 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
962 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
963 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
964 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
965 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
966 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TYMS [1] TYMS 💬 |
D01223 D01223 💬 |
Capecitabine | 094 [1] 94 💬 |
967 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TYMS [1] TYMS 💬 |
D01244 D01244 💬 |
Tegafur | 046 [1] 46 💬 |
968 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
CD74 [1] CD74 💬 |
D08944 D08944 💬 |
Milatuzumab | 049 [1] 49 💬 |
969 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
970 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
971 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
972 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
973 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
974 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
975 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
976 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
977 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
978 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
979 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
980 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
981 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
982 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
983 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
984 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
985 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
986 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
987 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
988 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
989 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
990 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
991 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
992 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
993 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
994 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
CCN2 [1] CCN2 💬 |
D10969 D10969 💬 |
Pamrevlumab | 085 [2] 85, 113 💬 |
995 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
HDAC4 [2] HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
996 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
997 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
998 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
999 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1000 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1001 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1002 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
1003 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
1004 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
1005 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
1006 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1007 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1008 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
1009 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
1010 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
1011 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
1012 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
1013 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
1014 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
1015 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
1016 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
1017 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
1018 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
1019 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
1020 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1021 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1022 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
1023 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1024 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1025 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
1026 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
1027 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
CTSC [1] CTSC 💬 |
D12120 D12120 💬 |
Brensocatib | 299 [1] 299 💬 |
1028 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
1029 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
1030 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
1031 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1032 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1033 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
1034 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
1035 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
PARP1 [2] PARP1, PARP2 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
1036 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
1037 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
1038 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1039 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1040 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
1041 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
1042 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
1043 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
1044 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
1045 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
1046 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
1047 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
1048 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
1049 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
1050 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
1051 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1052 | Apoptosis - multiple species 💬 Related to 3 target genes, 3 drugs (DrugBank) and 9 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
1053 | Apoptosis - multiple species 💬 Related to 3 target genes, 3 drugs (DrugBank) and 9 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
1054 | Apoptosis - multiple species 💬 Related to 3 target genes, 3 drugs (DrugBank) and 9 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
1055 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 [1] 113 💬 |
1056 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
1057 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGES [3] PTGES, PTGS1, PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
1058 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
1059 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1060 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
1061 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
1062 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
1063 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
1064 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
1065 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
1066 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
1067 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
1068 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
1069 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
1070 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
1071 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
1072 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
1073 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
1074 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
1075 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
1076 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
1077 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
1078 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
1079 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
1080 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
1081 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
1082 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
1083 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
1084 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
1085 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
1086 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
1087 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
1088 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
1089 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
1090 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
1091 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
1092 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
1093 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
1094 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
1095 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
1096 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
1097 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
1098 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
1099 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
1100 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
1101 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
1102 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
1103 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
ODC1 [1] ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 [1] 65 💬 |
1104 | Arginine biosynthesis 💬 Related to 1 target gene, 1 drug (DrugBank) and 3 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
1105 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
1106 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
1107 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
1108 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
1109 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1110 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1111 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1112 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
1113 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1114 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1115 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
1116 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
1117 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
1118 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
1119 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
1120 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
1121 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1122 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1123 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
D11203 D11203 💬 |
Mirogabalin | 070 [1] 70 💬 |
1124 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
1125 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
1126 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
DMD [1] DMD 💬 |
D11988 D11988 💬 |
Casimersen | 113 [1] 113 💬 |
1127 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
DMD [1] DMD 💬 |
D10114 D10114 💬 |
Drisapersen | 113 [1] 113 💬 |
1128 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
DMD [1] DMD 💬 |
D09900 D09900 💬 |
Eteplirsen | 113 [1] 113 💬 |
1129 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
DMD [1] DMD 💬 |
D11707 D11707 💬 |
Golodirsen | 113 [1] 113 💬 |
1130 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
DMD [1] DMD 💬 |
D11528 D11528 💬 |
Viltolarsen | 113 [1] 113 💬 |
1131 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
1132 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
1133 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
1134 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
1135 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
1136 | Ascorbate and aldarate metabolism 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
GUSB [1] GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 [1] 19 💬 |
1137 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
1138 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
1139 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
1140 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
1141 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
FCER1A [1] FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬 |
1142 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1143 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
1144 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL13 [1] IL13 💬 |
D08857 D08857 💬 |
Anrukinzumab | 097 [1] 97 💬 |
1145 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL13 [1] IL13 💬 |
D09633 D09633 💬 |
Lebrikizumab | 085 [1] 85 💬 |
1146 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL13 [1] IL13 💬 |
D09979 D09979 💬 |
Tralokinumab | 085 [2] 85, 97 💬 |
1147 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
1148 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
1149 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
1150 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
1151 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
1152 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
1153 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
1154 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
1155 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
1156 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
1157 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
1158 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
1159 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1160 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
1161 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
1162 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
1163 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
1164 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1165 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
1166 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 [1] 159 💬 |
1167 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
1168 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1169 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
1170 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
1171 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IL10 [1] IL10 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
1172 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
1173 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
1174 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
1175 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
TPO [1] TPO 💬 |
D00401 D00401 💬 |
Methimazole | 050 [1] 50 💬 |
1176 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
1177 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
1178 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1179 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1180 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
1181 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
1182 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
1183 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
1184 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1185 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1186 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1187 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
1188 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
1189 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
1190 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1191 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1192 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
PRKCD [2] PRKCD, PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
1193 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1194 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1195 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1196 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1197 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
1198 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
1199 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
1200 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
1201 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
1202 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
1203 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1204 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
1205 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
BMPR2 [1] BMPR2 💬 |
D03779 D03779 💬 |
Dibotermin alfa | 034 [1] 34 💬 |
1206 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [6] 19, 20, 51, 65, 285, 299 💬 |
1207 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
EPHB4 [1] EPHB4 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
1208 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
1209 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
1210 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
1211 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
1212 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
1213 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
1214 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
1215 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
1216 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1217 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1218 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
RGMA [1] RGMA 💬 |
D11355 D11355 💬 |
Elezanumab | 013 [1] 13 💬 |
1219 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
1220 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |
1221 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
SMO [1] SMO 💬 |
D10671 D10671 💬 |
Taladegib | 085 [1] 85 💬 |
1222 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
SMO [1] SMO 💬 |
D09992 D09992 💬 |
Vismodegib | 085 [1] 85 💬 |