Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
2 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
3 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
4 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
5 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
6 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CDK4 [1] CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
7 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
8 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 [1] 159 💬 |
9 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
10 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
FYN [2] FYN, LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
11 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
FYN [2] FYN, LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
12 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
13 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
14 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
15 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
16 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
17 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
18 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
19 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
20 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
21 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
22 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
23 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
24 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
25 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
26 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10574 D10574 💬 |
Pembrolizumab | 025 [2] 25, 285 💬 |
27 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
28 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
29 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
30 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
31 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
32 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
33 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
34 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PRKCQ [1] PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
35 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
36 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
37 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
38 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
39 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
40 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
41 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
42 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
43 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
44 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
45 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
46 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
47 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
48 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
49 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
50 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
51 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
52 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
53 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
54 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
55 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
56 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
57 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
58 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
59 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
60 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
61 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
62 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
63 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
64 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [2] CACNA1C, CHRM3 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
65 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
66 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
67 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [2] 2 , 299 💬 |
68 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [2] 2 , 299 💬 |
69 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [2] 2 , 299 💬 |
70 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [2] 2 , 299 💬 |
71 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01000 D01000 💬 |
Bethanechol | 098 [1] 98 💬 |
72 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
73 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00661 D00661 💬 |
Cevimeline | 053 [1] 53 💬 |
74 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
75 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
76 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
77 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
78 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
79 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01699 D01699 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
80 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
81 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
82 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
83 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
84 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
85 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
86 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
87 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
88 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00481 D00481 💬 |
Propantheline | 026 [1] 26 💬 |
89 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
90 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
91 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01269 D01269 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
92 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
93 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
94 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01148 D01148 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
95 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
96 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
97 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [3] 6 , 13, 19 💬 |
98 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
99 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
100 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [7] 2 , 10, 13, 18, 65, 149, 206 💬 |
101 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [1] GABRA1 💬 |
D00548 D00548 💬 |
Etomidate | 006 [1] 6 💬 |
102 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00225 D00225 💬 |
Alprazolam | 008 [2] 8 , 75 💬 |
103 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D11149 D11149 💬 |
Brexanolone | 205 [1] 205 💬 |
104 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00267 D00267 💬 |
Chlordiazepoxide | 046 [1] 46 💬 |
105 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00693 D00693 💬 |
Chlordiazepoxide | 046 [1] 46 💬 |
106 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
107 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00280 D00280 💬 |
Clonazepam | 006 [1] 6 💬 |
108 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D07784 D07784 💬 |
Delorazepam | 006 [3] 6 , 46, 97 💬 |
109 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
110 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D02624 D02624 💬 |
Eszopiclone | 006 [3] 6 , 13, 46 💬 |
111 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D01514 D01514 💬 |
Etizolam | 046 [1] 46 💬 |
112 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00697 D00697 💬 |
Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬 |
113 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 [2] 201, 206 💬 |
114 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 [4] 145, 152, 158, 206 💬 |
115 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00365 D00365 💬 |
Lorazepam | 036 [2] 36, 231 💬 |
116 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
117 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00696 D00696 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
118 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D05028 D05028 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
119 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00549 D00549 💬 |
Propofol | 006 [10] 6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬 |
120 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00706 D00706 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
121 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D08690 D08690 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
122 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D01372 D01372 💬 |
Zopiclone | 006 [1] 6 💬 |
123 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
124 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D00702 D00702 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
125 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D07593 D07593 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
126 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
127 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
128 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1A [6] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D10184 D10184 💬 |
Vortioxetine | 006 [1] 6 💬 |
129 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR1B [2] HTR1B, HTR1D 💬 |
D00415 D00415 💬 |
Zolmitriptan | 006 [1] 6 💬 |
130 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [1] HTR3A 💬 |
D00274 D00274 💬 |
Cisapride | 013 [1] 13 💬 |
131 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [1] HTR3A 💬 |
D02092 D02092 💬 |
Cisapride | 013 [1] 13 💬 |
132 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00283 D00283 💬 |
Clozapine | 006 [1] 6 💬 |
133 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00456 D00456 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
134 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
HTR3A [5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 |
D00678 D00678 💬 |
Ondansetron | 006 [4] 6 , 97, 107, 231 💬 |
135 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
P2RX3 [1] P2RX3 💬 |
D11349 D11349 💬 |
Gefapixant | 085 [2] 85, 226 💬 |
136 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
137 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
138 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
139 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
140 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
141 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
142 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
143 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
144 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
145 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
146 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1B [1] PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
147 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1B [1] PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
148 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
149 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
150 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D01450 D01450 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
151 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
152 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00252 D00252 💬 |
Carbamazepine | 013 [2] 13, 231 💬 |
153 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D03492 D03492 💬 |
Cibenzoline | 058 [1] 58 💬 |
154 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D11155 D11155 💬 |
Eleclazine | 058 [1] 58 💬 |
155 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00638 D00638 💬 |
Flecainide | 006 [1] 6 💬 |
156 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D07962 D07962 💬 |
Flecainide | 006 [1] 6 💬 |
157 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00354 D00354 💬 |
Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬 |
158 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D01287 D01287 💬 |
Levobupivacaine | 046 [1] 46 💬 |
159 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08116 D08116 💬 |
Levobupivacaine | 046 [1] 46 💬 |
160 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
161 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
162 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [13] 6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬 |
163 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
164 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
165 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00533 D00533 💬 |
Oxcarbazepine | 013 [1] 13 💬 |
166 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D01768 D01768 💬 |
Oxybuprocaine | 006 [1] 6 💬 |
167 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08319 D08319 💬 |
Oxybuprocaine | 006 [1] 6 💬 |
168 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00512 D00512 💬 |
Phenytoin | 013 [1] 13 💬 |
169 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02103 D02103 💬 |
Phenytoin | 013 [1] 13 💬 |
170 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00642 D00642 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
171 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00643 D00643 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
172 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02272 D02272 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
173 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08458 D08458 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
174 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D04048 D04048 💬 |
Ropivacaine | 036 [3] 36, 46, 70 💬 |
175 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08490 D08490 💬 |
Ropivacaine | 036 [3] 36, 46, 70 💬 |
176 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D05775 D05775 💬 |
Rufinamide | 144 [1] 144 💬 |
177 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
178 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN3A [2] SCN3A, SCN9A 💬 |
D07299 D07299 💬 |
Lacosamide | 002 [3] 2 , 46, 149 💬 |
179 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCNN1A [3] SCNN1A, SCNN1B, SCNN1G 💬 |
D00649 D00649 💬 |
Amiloride | 013 [4] 13, 67, 225, 299 💬 |
180 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCNN1A [3] SCNN1A, SCNN1B, SCNN1G 💬 |
D07447 D07447 💬 |
Amiloride | 013 [4] 13, 67, 225, 299 💬 |
181 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
182 | Taurine and hypotaurine metabolism 💬 Related to 2 target genes, 1 drug (DrugBank) and 17 diseases in DDrare |
GAD1 [2] GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
183 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
184 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
185 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
186 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 |
187 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 |
188 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
189 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
190 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
191 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
192 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
193 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
194 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
195 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FNTA [2] FNTA, FNTB 💬 |
D04768 D04768 💬 |
Lonafarnib | 113 [2] 113, 333 💬 |
196 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
FNTA [2] FNTA, FNTB 💬 |
D03720 D03720 💬 |
Tipifarnib | 034 [1] 34 💬 |
197 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
198 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
199 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00892 D00892 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
200 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
201 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
202 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
203 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
204 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
205 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
206 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
207 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
208 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
ACVR2A [2] ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 [1] 15 💬 |
209 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
BMPR2 [1] BMPR2 💬 |
D03779 D03779 💬 |
Dibotermin alfa | 034 [1] 34 💬 |
210 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
211 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
212 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
RGMA [1] RGMA 💬 |
D11355 D11355 💬 |
Elezanumab | 013 [1] 13 💬 |
213 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
ROCK1 [1] ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
214 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
SMAD7 [1] SMAD7 💬 |
D10956 D10956 💬 |
Mongersen | 096 [2] 96, 97 💬 |
215 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
216 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
217 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
218 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
219 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
220 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
221 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
222 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
223 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
224 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
225 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
226 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
227 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
228 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
229 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
230 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
231 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
232 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
233 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
234 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
235 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
236 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL13 [1] IL13 💬 |
D08857 D08857 💬 |
Anrukinzumab | 097 [1] 97 💬 |
237 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL13 [1] IL13 💬 |
D09633 D09633 💬 |
Lebrikizumab | 085 [1] 85 💬 |
238 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL13 [1] IL13 💬 |
D09979 D09979 💬 |
Tralokinumab | 085 [2] 85, 97 💬 |
239 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
240 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
241 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
242 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
243 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
244 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
245 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
246 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
247 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
248 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
249 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
250 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
251 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
252 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
253 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
LCK [1] LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
254 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
LCK [1] LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
255 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
256 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
257 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
258 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
259 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
260 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
261 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
262 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
263 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PRKCQ [1] PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
264 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
265 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 [2] 96, 97 💬 |
266 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
267 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
268 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
269 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
270 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
271 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
272 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
273 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
274 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
275 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
276 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D11127 D11127 💬 |
Tibulizumab | 053 [1] 53 💬 |
277 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [2] IL17A, IL17F 💬 |
D11550 D11550 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 |
278 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
279 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
280 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
281 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
282 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
283 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL22 [1] IL22 💬 |
D11953 D11953 💬 |
Efmarodocokin alfa | 096 [2] 96, 97 💬 |
284 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
285 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 |
286 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
287 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
288 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10400 D10400 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 |
289 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
290 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
291 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
292 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
293 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
294 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
295 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
296 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
297 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
298 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
299 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 [2] 11, 13 💬 |
300 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
301 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
302 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
303 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
304 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
305 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
306 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
307 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
308 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
LCK [1] LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
309 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
LCK [1] LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
310 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
311 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
312 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
313 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
314 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
315 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
316 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
317 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
318 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
319 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
320 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
321 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PRKCQ [1] PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
322 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [1] RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 [1] 299 💬 |
323 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
324 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
325 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [1] RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
326 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [1] RARA 💬 |
D06543 D06543 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 |
327 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
328 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
329 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
330 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
331 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
332 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 [2] 96, 97 💬 |
333 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
334 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
335 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
336 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
337 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
338 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
339 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
340 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
341 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
342 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
343 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
344 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
345 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
346 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
347 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
348 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
349 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
350 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05099 D05099 💬 |
Nabilone | 006 [2] 6 , 13 💬 |
351 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 [1] 193 💬 |
352 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
353 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
354 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
FGFR1 [1] FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
355 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
FGFR1 [1] FGFR1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
356 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
357 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
358 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
359 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
360 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
361 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
362 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
363 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
364 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
365 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
366 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
367 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
368 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
369 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
370 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
371 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
372 | Thiamine metabolism 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
ALPL [1] ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 [1] 172 💬 |
373 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
374 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
BRAF [2] BRAF, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
375 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
BRAF [2] BRAF, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
376 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
377 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
378 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
379 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
380 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
381 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
382 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
383 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
384 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
385 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
386 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
RET [1] RET 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
387 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
RET [1] RET 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
388 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
389 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
390 | Thyroid cancer 💬 Related to 8 target genes, 14 drugs (DrugBank) and 27 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
391 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
392 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
393 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
394 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
395 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
396 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
397 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
398 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
399 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
400 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
401 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01413 D01413 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
402 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01617 D01617 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
403 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01953 D01953 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
404 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D04061 D04061 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
405 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D04063 D04063 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
406 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D04064 D04064 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
407 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D04065 D04065 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
408 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
409 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
410 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
411 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 |
412 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
413 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
414 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
415 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D02217 D02217 💬 |
Raloxifene | 046 [1] 46 💬 |
416 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
417 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
418 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
419 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
HDAC1 [3] HDAC1, HDAC2, HDAC3 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
420 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
421 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
422 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
423 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
424 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
425 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
426 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
427 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
428 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
429 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
430 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
431 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
432 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
433 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
434 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
435 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
436 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
437 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
438 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
439 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA [2] THRA, THRB 💬 |
D01010 D01010 💬 |
Levothyroxine | 019 [5] 19, 49, 78, 80, 222 💬 |
440 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA [2] THRA, THRB 💬 |
D08125 D08125 💬 |
Levothyroxine | 019 [5] 19, 49, 78, 80, 222 💬 |
441 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA [2] THRA, THRB 💬 |
D01011 D01011 💬 |
Liothyronine | 013 [4] 13, 78, 210, 212 💬 |
442 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA [2] THRA, THRB 💬 |
D08128 D08128 💬 |
Liothyronine | 013 [4] 13, 78, 210, 212 💬 |
443 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRA [2] THRA, THRB 💬 |
D07214 D07214 💬 |
Tiratricol | 078 [2] 78, 139 💬 |
444 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
THRB [1] THRB 💬 |
D09381 D09381 💬 |
Sobetirome | 020 [1] 20 💬 |
445 | Thyroid hormone synthesis 💬 Related to 6 target genes, 5 drugs (DrugBank) and 6 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
446 | Thyroid hormone synthesis 💬 Related to 6 target genes, 5 drugs (DrugBank) and 6 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
447 | Thyroid hormone synthesis 💬 Related to 6 target genes, 5 drugs (DrugBank) and 6 diseases in DDrare |
TPO [1] TPO 💬 |
D00401 D00401 💬 |
Methimazole | 050 [1] 50 💬 |
448 | Thyroid hormone synthesis 💬 Related to 6 target genes, 5 drugs (DrugBank) and 6 diseases in DDrare |
TTR [1] TTR 💬 |
D10940 D10940 💬 |
Inotersen | 028 [1] 28 💬 |
449 | Thyroid hormone synthesis 💬 Related to 6 target genes, 5 drugs (DrugBank) and 6 diseases in DDrare |
TTR [1] TTR 💬 |
D09673 D09673 💬 |
Tafamidis | 028 [1] 28 💬 |
450 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
451 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
452 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
453 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
454 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
455 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
456 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
457 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
458 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
459 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
460 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
461 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
462 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
463 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
464 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
465 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
466 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
467 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
468 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CDK4 [1] CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
469 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
470 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
471 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
472 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
473 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
474 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
475 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
476 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
477 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
478 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
479 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
480 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
481 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
482 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
483 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |
484 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
485 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
486 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
487 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
488 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
489 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
490 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
491 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
492 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
493 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
494 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
495 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
496 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
497 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
498 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
LTA [1] LTA 💬 |
D10187 D10187 💬 |
Pateclizumab | 046 [1] 46 💬 |
499 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
500 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
501 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
502 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
503 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
504 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
505 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
506 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
507 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
508 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
509 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
510 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
511 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
512 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
513 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
514 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
515 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
516 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
517 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
518 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
519 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
520 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
521 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
522 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
523 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
524 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
525 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
526 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
527 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
528 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
529 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
530 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
531 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
532 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
533 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
534 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
535 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
536 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
537 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
538 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
539 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
540 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
541 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
542 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
543 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
544 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
545 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
546 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
547 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
548 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
549 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
550 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
551 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
552 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
553 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
554 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
555 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
556 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
557 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
558 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
559 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
560 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 [2] 46, 49 💬 |
561 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
562 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 [1] 56 💬 |
563 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 |
564 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
565 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 [1] 13 💬 |
566 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 |
567 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
568 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
569 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
570 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
571 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
572 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
573 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
574 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
575 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
576 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
577 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
578 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
579 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
580 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
581 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
582 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
583 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
584 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
585 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TLR7 [1] TLR7 💬 |
D02500 D02500 💬 |
Imiquimod | 034 [2] 34, 51 💬 |
586 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
587 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
588 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
589 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
590 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
591 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
592 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
593 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
594 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
595 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 [1] 113 💬 |
596 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
597 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
598 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
599 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
600 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
601 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
602 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
603 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
604 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
605 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
606 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
607 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
608 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
609 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
610 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
611 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
612 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
613 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
614 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
615 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
616 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
617 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
618 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
619 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
620 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
621 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
622 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
623 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
624 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
625 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
626 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
627 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
628 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
629 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
630 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
631 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
632 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
633 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 [2] 96, 97 💬 |
634 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
635 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
636 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
637 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
638 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 [1] CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
639 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CSF1R [2] CSF1R, FLT3 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
640 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
641 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
ELANE [1] ELANE 💬 |
D03788 D03788 💬 |
Sivelestat | 013 [3] 13, 85, 96 💬 |
642 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
643 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
644 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
645 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT1 [2] FLT1, FLT3 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
646 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT1 [2] FLT1, FLT3 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
647 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT3 [1] FLT3 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
648 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
FLT3 [1] FLT3 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
649 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
GRIA3 [1] GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
650 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
GRIA3 [1] GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
651 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
GRIA3 [1] GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
652 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
GRIA3 [1] GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
653 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
654 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
655 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
656 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
657 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
658 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
659 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL2RB [1] IL2RB 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
660 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
661 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
662 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
663 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
664 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
665 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
666 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
667 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
668 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [3] 2 , 17, 127 💬 |
669 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
670 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
671 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PML [2] PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
672 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
673 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
674 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
675 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
676 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
677 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
678 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [1] RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 [1] 299 💬 |
679 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
680 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
681 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [1] RARA 💬 |
D06543 D06543 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 |
682 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
683 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
684 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
685 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
686 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
687 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
688 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
689 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
690 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
691 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
692 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
693 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
694 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
695 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
696 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
697 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
698 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
699 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
700 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
TPH1 [2] TPH1, TPH2 💬 |
D09973 D09973 💬 |
Telotristat | 097 [1] 97 💬 |
701 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
702 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [3] 2 , 62, 222 💬 |
703 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
704 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
CD74 [1] CD74 💬 |
D08944 D08944 💬 |
Milatuzumab | 049 [1] 49 💬 |
705 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
706 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
707 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
708 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
709 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
710 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
711 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
712 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
713 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
714 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
715 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
716 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
717 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
718 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 |
719 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
720 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
721 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10400 D10400 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 |
722 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
723 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
724 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
725 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
726 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
727 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
728 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
729 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
730 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
731 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
732 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
733 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
734 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
735 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
736 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
737 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
738 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
739 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
740 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
741 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
742 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
743 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
744 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
745 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
746 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
747 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
748 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
749 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
750 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
751 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
752 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
753 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
754 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
755 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
756 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
757 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
758 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
759 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 [2] 113, 299 💬 |
760 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D01125 D01125 💬 |
Calcipotriol | 036 [2] 36, 51 💬 |
761 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
762 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [25] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
763 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00299 D00299 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 |
764 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D07578 D07578 💬 |
Eldecalcitol | 046 [1] 46 💬 |
765 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 |
766 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [4] 19, 66, 218, 238 💬 |
767 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
768 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
769 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
GAD1 [2] GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
770 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
771 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
772 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
773 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
774 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
775 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
776 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
777 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
778 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
779 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
LTA [1] LTA 💬 |
D10187 D10187 💬 |
Pateclizumab | 046 [1] 46 💬 |
780 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
781 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
782 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
783 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
784 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
785 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
786 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
787 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
788 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
789 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
790 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
ABCC8 [2] ABCC8, KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 [2] 13, 193 💬 |
791 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
ABCC8 [2] ABCC8, KCNJ11 💬 |
D00418 D00418 💬 |
Minoxidil | 179 [1] 179 💬 |
792 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
ABCC8 [2] ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 [3] 6 , 21, 299 💬 |
793 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1B [3] CACNA1B, CACNA1C, CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
794 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
795 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
796 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
797 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
798 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
799 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
800 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
801 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
802 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
803 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
804 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
805 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
806 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
807 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
808 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
809 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
810 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
811 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
812 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
813 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
814 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
815 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
816 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
817 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
818 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
819 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
KCNJ11 [1] KCNJ11 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
820 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
KCNJ11 [1] KCNJ11 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
821 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
822 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
823 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
824 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
825 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
826 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
PRKCD [2] PRKCD, PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
827 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
828 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
829 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
830 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
831 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
832 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
833 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
834 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
835 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
836 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
837 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
838 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
839 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
AOC3 [1] AOC3 💬 |
D08044 D08044 💬 |
Hydralazine | 067 [1] 67 💬 |
840 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
COMT [1] COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 [2] 6 , 17 💬 |
841 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
COMT [1] COMT 💬 |
D10825 D10825 💬 |
Opicapone | 006 [1] 6 💬 |
842 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
COMT [1] COMT 💬 |
D00786 D00786 💬 |
Tolcapone | 006 [3] 6 , 28, 127 💬 |
843 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
844 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
845 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
HPD [1] HPD 💬 |
D05177 D05177 💬 |
Nitisinone | 006 [3] 6 , 164, 241 💬 |
846 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
847 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
848 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
849 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
850 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
851 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
852 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
853 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
854 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
855 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
856 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
857 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
858 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
TPO [1] TPO 💬 |
D00401 D00401 💬 |
Methimazole | 050 [1] 50 💬 |