Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Valine, leucine and isoleucine degradation 💬
[1] ABAT 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
2 Valine, leucine and isoleucine degradation 💬
[1] ABAT 💬 D00535 💬 Vigabatrin [2] 145, 158 💬
3 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
4 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
5 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D04641 💬 Istradefylline [1]  6  💬
6 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D09717 💬 Preladenant [1]  6  💬
7 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D05711 💬 Regadenoson [1] 58 💬
8 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D02017 💬 Theophylline [2] 236, 299 💬
9 Vascular smooth muscle contraction 💬
[1] ADORA2A 💬 D10174 💬 Tozadenant [1]  6  💬
10 Vascular smooth muscle contraction 💬
[2] ADORA2A, ADORA2B 💬 D00045 💬 Adenosine [3] 13, 58, 65 💬
11 Vascular smooth muscle contraction 💬
[2] ADORA2A, ADORA2B 💬 D02769 💬 Adenosine phosphate [1] 46 💬
12 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D00227 💬 Aminophylline [1] 63 💬
13 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D05429 💬 Aminophylline [1] 63 💬
14 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D00371 💬 Theophylline [2] 236, 299 💬
15 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D01712 💬 Theophylline [2] 236, 299 💬
16 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D06103 💬 Theophylline [2] 236, 299 💬
17 Vascular smooth muscle contraction 💬
[1] ADORA2B 💬 D06104 💬 Theophylline [2] 236, 299 💬
18 Vascular smooth muscle contraction 💬
[1] ADRA1A 💬 D01692 💬 Alfuzosin [1] 13 💬
19 Vascular smooth muscle contraction 💬
[1] ADRA1A 💬 D07124 💬 Alfuzosin [1] 13 💬
20 Vascular smooth muscle contraction 💬
[1] ADRA1A 💬 D01965 💬 Silodosin [2]  6 , 13 💬
21 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00636 💬 Amiodarone [2] 28, 127 💬
22 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D02910 💬 Amiodarone [2] 28, 127 💬
23 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
24 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
25 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D02349 💬 Dipivefrin [1]  6  💬
26 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
27 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
28 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
29 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00124 💬 Ephedrine [1] 11 💬
30 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
31 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
32 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
33 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D02268 💬 Ergoloid mesylate [2]  6 , 206 💬
34 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08064 💬 Ifenprodil [1] 85 💬
35 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00680 💬 Methylergometrine [3] 118, 280, 288 💬
36 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08207 💬 Methylergometrine [3] 118, 280, 288 💬
37 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D01307 💬 Midodrine [3]  6 , 17, 58 💬
38 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08220 💬 Midodrine [3]  6 , 17, 58 💬
39 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00076 💬 Norepinephrine [1] 22 💬
40 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D05206 💬 Norepinephrine [1] 22 💬
41 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
42 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D06623 💬 Olanzapine [2]  2 ,  8  💬
43 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00511 💬 Phenylephrine [1] 22 💬
44 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine [1] 22 💬
45 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00485 💬 Pseudoephedrine [1] 17 💬
46 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D05648 💬 Pseudoephedrine [1] 17 💬
47 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D05649 💬 Pseudoephedrine [1] 17 💬
48 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08449 💬 Pseudoephedrine [1] 17 💬
49 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00610 💬 Terazosin [1]  6  💬
50 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D08569 💬 Terazosin [1]  6  💬
51 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
52 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
53 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00522 💬 Candesartan [2] 58, 67 💬
54 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00522 💬 Candesartan cilexetil [1] 67 💬
55 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00626 💬 Candesartan cilexetil [1] 67 💬
56 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00523 💬 Irbesartan [4] 66, 167, 168, 222 💬
57 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00357 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
58 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D08146 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
59 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00627 💬 Telmisartan [2] 66, 67 💬
60 Vascular smooth muscle contraction 💬
[1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
61 Vascular smooth muscle contraction 💬
[2] AGTR1, EDNRA 💬 D11776 💬 Sparsentan [3] 66, 218, 222 💬
62 Vascular smooth muscle contraction 💬
[1] AVPR1A 💬 D01236 💬 Conivaptan [1] 86 💬
63 Vascular smooth muscle contraction 💬
[1] AVPR1A 💬 D07748 💬 Conivaptan [1] 86 💬
64 Vascular smooth muscle contraction 💬
[2] AVPR1A, AVPR1B 💬 D06672 💬 Terlipressin [1] 299 💬
65 Vascular smooth muscle contraction 💬
[2] AVPR1A, AVPR1B 💬 D00101 💬 Vasopressin [1] 210 💬
66 Vascular smooth muscle contraction 💬
[1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
67 Vascular smooth muscle contraction 💬
[2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
68 Vascular smooth muscle contraction 💬
[2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
69 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine [4] 13, 51, 67, 298 💬
70 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine [4] 13, 51, 67, 298 💬
71 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
72 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
73 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem [3] 51, 58, 86 💬
74 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem [3] 51, 58, 86 💬
75 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
76 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
77 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine [2] 70, 86 💬
78 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
79 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
80 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
81 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline [2] 58, 272 💬
82 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
83 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
84 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
85 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil [3] 96, 140, 167 💬
86 Vascular smooth muscle contraction 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [3] 96, 140, 167 💬
87 Vascular smooth muscle contraction 💬
[1] CALCA 💬 D11055 💬 Fremanezumab [2] 124, 226 💬
88 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
89 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
90 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
91 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
92 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
93 Vascular smooth muscle contraction 💬
[1] EDNRA 💬 D07741 💬 Zibotentan [1] 51 💬
94 Vascular smooth muscle contraction 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
95 Vascular smooth muscle contraction 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
96 Vascular smooth muscle contraction 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
97 Vascular smooth muscle contraction 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
98 Vascular smooth muscle contraction 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
99 Vascular smooth muscle contraction 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
100 Vascular smooth muscle contraction 💬
[1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
101 Vascular smooth muscle contraction 💬
[2] NPR1, NPR2 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
102 Vascular smooth muscle contraction 💬
[1] NPR2 💬 D11190 💬 Vosoritide [1] 276 💬
103 Vascular smooth muscle contraction 💬
[4] PRKCD, PRKCE, PRKCH, PRKCQ 💬 D09671 💬 Sotrastaurin [1] 97 💬
104 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D02720 💬 Beraprost [1] 86 💬
105 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D00106 💬 Epoprostenol [1] 86 💬
106 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D01337 💬 Epoprostenol [1] 86 💬
107 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
108 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
109 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D10725 💬 Ralinepag [1] 86 💬
110 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D09994 💬 Selexipag [6] 47, 51, 70, 84, 86, 88 💬
111 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
112 Vascular smooth muscle contraction 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
113 Vascular smooth muscle contraction 💬
[1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬
114 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D01236 💬 Conivaptan [1] 86 💬
115 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D07748 💬 Conivaptan [1] 86 💬
116 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
117 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
118 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D04752 💬 Lixivaptan [1] 67 💬
119 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D06672 💬 Terlipressin [1] 299 💬
120 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
121 Vasopressin-regulated water reabsorption 💬
[1] AVPR2 💬 D00101 💬 Vasopressin [1] 210 💬
122 VEGF signaling pathway 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
123 VEGF signaling pathway 💬
[1] KDR 💬 D03218 💬 Axitinib [1] 34 💬
124 VEGF signaling pathway 💬
[1] KDR 💬 D10062 💬 Cabozantinib [1] 34 💬
125 VEGF signaling pathway 💬
[1] KDR 💬 D08881 💬 Cediranib [1] 34 💬
126 VEGF signaling pathway 💬
[1] KDR 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
127 VEGF signaling pathway 💬
[1] KDR 💬 D06402 💬 Sunitinib [2] 28, 34 💬
128 VEGF signaling pathway 💬
[1] KDR 💬 D08552 💬 Sunitinib [2] 28, 34 💬
129 VEGF signaling pathway 💬
[1] KDR 💬 D11772 💬 Tesevatinib [1] 67 💬
130 VEGF signaling pathway 💬
[2] KDR, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
131 VEGF signaling pathway 💬
[2] KDR, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
132 VEGF signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
133 VEGF signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
134 VEGF signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
135 VEGF signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
136 VEGF signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
137 VEGF signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
138 VEGF signaling pathway 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
139 VEGF signaling pathway 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
140 VEGF signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
141 VEGF signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
142 VEGF signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
143 VEGF signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
144 VEGF signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [1] 222 💬
145 VEGF signaling pathway 💬
[1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
146 VEGF signaling pathway 💬
[1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
147 VEGF signaling pathway 💬
[1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
148 VEGF signaling pathway 💬
[1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
149 VEGF signaling pathway 💬
[1] PTGS2 💬 D00903 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
150 VEGF signaling pathway 💬
[1] PTGS2 💬 D00904 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
151 VEGF signaling pathway 💬
[1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
152 VEGF signaling pathway 💬
[1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
153 VEGF signaling pathway 💬
[1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
154 VEGF signaling pathway 💬
[1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
155 VEGF signaling pathway 💬
[1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
156 VEGF signaling pathway 💬
[1] PTGS2 💬 D01475 💬 Flurbiprofen [3] 13, 21, 46 💬
157 VEGF signaling pathway 💬
[1] PTGS2 💬 D02290 💬 Flurbiprofen [3] 13, 21, 46 💬
158 VEGF signaling pathway 💬
[1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
159 VEGF signaling pathway 💬
[1] PTGS2 💬 D01122 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
160 VEGF signaling pathway 💬
[1] PTGS2 💬 D04490 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
161 VEGF signaling pathway 💬
[1] PTGS2 💬 D06606 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
162 VEGF signaling pathway 💬
[1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
163 VEGF signaling pathway 💬
[1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
164 VEGF signaling pathway 💬
[1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
165 VEGF signaling pathway 💬
[1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
166 VEGF signaling pathway 💬
[1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
167 VEGF signaling pathway 💬
[1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
168 VEGF signaling pathway 💬
[1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
169 VEGF signaling pathway 💬
[1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
170 VEGF signaling pathway 💬
[1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
171 VEGF signaling pathway 💬
[1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
172 VEGF signaling pathway 💬
[1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
173 VEGF signaling pathway 💬
[1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
174 VEGF signaling pathway 💬
[1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
175 VEGF signaling pathway 💬
[1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
176 VEGF signaling pathway 💬
[1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
177 VEGF signaling pathway 💬
[1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
178 VEGF signaling pathway 💬
[1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
179 VEGF signaling pathway 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
180 VEGF signaling pathway 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
181 VEGF signaling pathway 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
182 VEGF signaling pathway 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
183 VEGF signaling pathway 💬
[1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
184 VEGF signaling pathway 💬
[1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
185 VEGF signaling pathway 💬
[1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬
186 Vibrio cholerae infection 💬
[1] CFTR 💬 D11423 💬 Deutivacaftor [1] 299 💬
187 Vibrio cholerae infection 💬
[1] CFTR 💬 D11507 💬 Elexacaftor [1] 299 💬
188 Vibrio cholerae infection 💬
[1] CFTR 💬 D11724 💬 Galicaftor [1] 299 💬
189 Vibrio cholerae infection 💬
[1] CFTR 💬 D09916 💬 Ivacaftor [1] 299 💬
190 Vibrio cholerae infection 💬
[1] CFTR 💬 D10134 💬 Lumacaftor [1] 299 💬
191 Vibrio cholerae infection 💬
[1] CFTR 💬 D11041 💬 Tezacaftor [1] 299 💬
192 Vibrio cholerae infection 💬
[1] KCNQ1 💬 D00636 💬 Amiodarone [2] 28, 127 💬
193 Vibrio cholerae infection 💬
[1] KCNQ1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
194 Vibrio cholerae infection 💬
[1] KCNQ1 💬 D09569 💬 Ezogabine [2]  2 , 144 💬
195 Vibrio cholerae infection 💬
[1] SLC12A2 💬 D00247 💬 Bumetanide [2]  6 , 158 💬
196 Vibrio cholerae infection 💬
[1] SLC12A2 💬 D00331 💬 Furosemide [1]  6  💬
197 Viral carcinogenesis 💬
[1] C3 💬 D11613 💬 Pegcetacoplan [3]  2 , 62, 222 💬
198 Viral carcinogenesis 💬
[1] CCR4 💬 D09761 💬 Mogamulizumab [1] 26 💬
199 Viral carcinogenesis 💬
[1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
200 Viral carcinogenesis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
201 Viral carcinogenesis 💬
[2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
202 Viral carcinogenesis 💬
[11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
203 Viral carcinogenesis 💬
[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
204 Viral carcinogenesis 💬
[1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
205 Viral carcinogenesis 💬
[1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
206 Viral carcinogenesis 💬
[1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
207 Viral carcinogenesis 💬
[1] JAK1 💬 D09959 💬 Ruxolitinib [1] 228 💬
208 Viral carcinogenesis 💬
[1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
209 Viral carcinogenesis 💬
[2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
210 Viral carcinogenesis 💬
[2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
211 Viral carcinogenesis 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
212 Viral carcinogenesis 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
213 Viral carcinogenesis 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
214 Viral carcinogenesis 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
215 Viral carcinogenesis 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
216 Viral carcinogenesis 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
217 Viral carcinogenesis 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
218 Viral carcinogenesis 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
219 Viral carcinogenesis 💬
[1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
220 Viral myocarditis 💬
[1] ABL1 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
221 Viral myocarditis 💬
[1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
222 Viral myocarditis 💬
[1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
223 Viral myocarditis 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
224 Viral myocarditis 💬
[1] ABL1 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
225 Viral myocarditis 💬
[2] ABL1, FYN 💬 D03658 💬 Dasatinib [2] 51, 85 💬
226 Viral myocarditis 💬
[2] ABL1, FYN 💬 D06414 💬 Dasatinib [2] 51, 85 💬
227 Viral myocarditis 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
228 Viral myocarditis 💬
[1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
229 Viral myocarditis 💬
[1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
230 Viral myocarditis 💬
[1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
231 Viral myocarditis 💬
[1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
232 Viral myocarditis 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
233 Viral myocarditis 💬
[2] CD80, CD86 💬 D03222 💬 Belatacept [1] 46 💬
234 Viral myocarditis 💬
[1] DMD 💬 D11988 💬 Casimersen [1] 113 💬
235 Viral myocarditis 💬
[1] DMD 💬 D10114 💬 Drisapersen [1] 113 💬
236 Viral myocarditis 💬
[1] DMD 💬 D09900 💬 Eteplirsen [1] 113 💬
237 Viral myocarditis 💬
[1] DMD 💬 D11707 💬 Golodirsen [1] 113 💬
238 Viral myocarditis 💬
[1] DMD 💬 D11528 💬 Viltolarsen [1] 113 💬
239 Viral myocarditis 💬
[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
240 Viral myocarditis 💬
[1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
241 Viral myocarditis 💬
[1] MYH7 💬 D12265 💬 Mavacamten [1] 58 💬
242 Viral protein interaction with cytokine and cytokine receptor 💬
[4] CCL2, IL10, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
243 Viral protein interaction with cytokine and cytokine receptor 💬
[2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
244 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CCR4 💬 D09761 💬 Mogamulizumab [1] 26 💬
245 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
246 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CSF1 💬 D06402 💬 Sunitinib [2] 28, 34 💬
247 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CSF1 💬 D08552 💬 Sunitinib [2] 28, 34 💬
248 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CSF1R 💬 D11270 💬 Pexidartinib [1] 34 💬
249 Viral protein interaction with cytokine and cytokine receptor 💬
[2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
250 Viral protein interaction with cytokine and cytokine receptor 💬
[1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
251 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL20 💬 D11756 💬 Fletikumab [1] 46 💬
252 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
253 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
254 Viral protein interaction with cytokine and cytokine receptor 💬
[3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
255 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
256 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
257 Viral protein interaction with cytokine and cytokine receptor 💬
[2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
258 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
259 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6R 💬 D11079 💬 Satralizumab [2] 11, 13 💬
260 Viral protein interaction with cytokine and cytokine receptor 💬
[1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
261 Viral protein interaction with cytokine and cytokine receptor 💬
[1] LTA 💬 D10187 💬 Pateclizumab [1] 46 💬
262 Viral protein interaction with cytokine and cytokine receptor 💬
[2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
263 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
264 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
265 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
266 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
267 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
268 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
269 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
270 Viral protein interaction with cytokine and cytokine receptor 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬