Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholic liver disease 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
2 Alcoholic liver disease 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
3 Alcoholic liver disease 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
4 Alcoholic liver disease 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
5 Complement and coagulation cascades 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
6 Complement and coagulation cascades 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
7 Complement and coagulation cascades 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
8 Complement and coagulation cascades 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
9 Complement and coagulation cascades 💬
[1] CFB 💬 D12251 💬 Iptacopan [5] 61, 62, 66, 109, 222 💬
10 Complement and coagulation cascades 💬
[1] MASP2 💬 D11531 💬 Narsoplimab [4] 64, 66, 109, 222 💬
11 Coronavirus disease - COVID-19 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
12 Coronavirus disease - COVID-19 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
13 Coronavirus disease - COVID-19 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
14 Coronavirus disease - COVID-19 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
15 Coronavirus disease - COVID-19 💬
[1] CFB 💬 D12251 💬 Iptacopan [5] 61, 62, 66, 109, 222 💬
16 Coronavirus disease - COVID-19 💬
[1] MASP2 💬 D11531 💬 Narsoplimab [4] 64, 66, 109, 222 💬
17 Herpes simplex virus 1 infection 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
18 Herpes simplex virus 1 infection 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
19 Herpes simplex virus 1 infection 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
20 Herpes simplex virus 1 infection 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
21 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
22 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
23 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
24 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
25 Neutrophil extracellular trap formation 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
26 Neutrophil extracellular trap formation 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
27 Neutrophil extracellular trap formation 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
28 Neutrophil extracellular trap formation 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
29 Pertussis 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
30 Pertussis 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
31 Pertussis 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
32 Pertussis 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
33 Prion disease 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
34 Prion disease 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
35 Prion disease 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
36 Prion disease 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
37 Staphylococcus aureus infection 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
38 Staphylococcus aureus infection 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
39 Staphylococcus aureus infection 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
40 Staphylococcus aureus infection 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
41 Staphylococcus aureus infection 💬
[1] CFB 💬 D12251 💬 Iptacopan [5] 61, 62, 66, 109, 222 💬
42 Staphylococcus aureus infection 💬
[1] MASP2 💬 D11531 💬 Narsoplimab [4] 64, 66, 109, 222 💬
43 Systemic lupus erythematosus 💬
[1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
44 Systemic lupus erythematosus 💬
[1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
45 Systemic lupus erythematosus 💬
[1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
46 Systemic lupus erythematosus 💬
[1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬