Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
2	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
3	Calcium signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
4	Calcium signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
5	Calcium signaling pathway 💬	[3] HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
6	cAMP signaling pathway 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
7	Circadian entrainment 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
8	Circadian entrainment 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
9	Circadian entrainment 💬	[2] MTNR1A, MTNR1B 💬	D08170 💬	Melatonin	[12] 6 , 8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬
10	Cortisol synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
11	Cortisol synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
12	Cushing syndrome 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
13	Cushing syndrome 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
14	ECM-receptor interaction 💬	[1] SV2A 💬	D08879 💬	Brivaracetam	[2] 149, 309 💬
15	ECM-receptor interaction 💬	[3] SV2A, SV2B, SV2C 💬	D11842 💬	Padsevonil	[1] 149 💬
16	Estrogen signaling pathway 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
17	GABAergic synapse 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
18	Gap junction 💬	[3] HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
19	GnRH secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
20	GnRH secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
21	GnRH secretion 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
22	Inflammatory mediator regulation of TRP channels 💬	[3] HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
23	Insulin secretion 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
24	MAPK signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
25	MAPK signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
26	Morphine addiction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
27	Neuroactive ligand-receptor interaction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
28	Neuroactive ligand-receptor interaction 💬	[3] HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
29	Neuroactive ligand-receptor interaction 💬	[2] MTNR1A, MTNR1B 💬	D08170 💬	Melatonin	[12] 6 , 8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬
30	Serotonergic synapse 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
31	Synaptic vesicle cycle 💬	[1] SLC6A4 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
32	Synaptic vesicle cycle 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
33	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[7] 2 , 10, 13, 18, 65, 149, 206 💬
34	Taste transduction 💬	[2] SCN3A, SCN9A 💬	D07299 💬	Lacosamide	[3] 2 , 46, 149 💬
35	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
36	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬