Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
2 Alcoholism 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
3 Alcoholism 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
4 Alzheimer disease 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
5 Amphetamine addiction 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
6 Amphetamine addiction 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
7 Amphetamine addiction 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
8 Arachidonic acid metabolism 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
9 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
10 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
11 Cocaine addiction 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
12 Cocaine addiction 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
13 Cocaine addiction 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
14 Dopaminergic synapse 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
15 Dopaminergic synapse 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
16 Dopaminergic synapse 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
17 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
18 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
19 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
20 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
21 Leishmaniasis 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
22 Metabolic pathways 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
23 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
24 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
25 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
26 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
27 Parkinson disease 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
28 Parkinson disease 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
29 Parkinson disease 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
30 Pathways in cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
31 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
32 Pathways of neurodegeneration - multiple diseases 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
33 Pathways of neurodegeneration - multiple diseases 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
34 Pathways of neurodegeneration - multiple diseases 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
35 Regulation of lipolysis in adipocytes 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
36 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
37 Serotonergic synapse 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
38 Small cell lung cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
39 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
40 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
41 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
42 TNF signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
43 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬

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