Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 AMPK signaling pathway 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
2 AMPK signaling pathway 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
3 Cytokine-cytokine receptor interaction 💬
[1] CSF2RA 💬 D05066 💬 Molgramostim [3] 97, 229, 299 💬
4 Cytokine-cytokine receptor interaction 💬
[1] CSF2RA 💬 D05712 💬 Regramostim [1] 229 💬
5 Cytokine-cytokine receptor interaction 💬
[1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
6 Hematopoietic cell lineage 💬
[1] CSF2RA 💬 D05066 💬 Molgramostim [3] 97, 229, 299 💬
7 Hematopoietic cell lineage 💬
[1] CSF2RA 💬 D05712 💬 Regramostim [1] 229 💬
8 Hematopoietic cell lineage 💬
[1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
9 Hematopoietic cell lineage 💬
[1] MS4A1 💬 D02994 💬 Rituximab [49]  6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
10 Huntington disease 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
11 Huntington disease 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
12 JAK-STAT signaling pathway 💬
[1] CSF2RA 💬 D05066 💬 Molgramostim [3] 97, 229, 299 💬
13 JAK-STAT signaling pathway 💬
[1] CSF2RA 💬 D05712 💬 Regramostim [1] 229 💬
14 JAK-STAT signaling pathway 💬
[1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
15 Lipid and atherosclerosis 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
16 Lipid and atherosclerosis 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
17 Longevity regulating pathway 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
18 Longevity regulating pathway 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
19 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
20 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
21 Osteoclast differentiation 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
22 Osteoclast differentiation 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
23 Pathways in cancer 💬
[1] CSF2RA 💬 D05066 💬 Molgramostim [3] 97, 229, 299 💬
24 Pathways in cancer 💬
[1] CSF2RA 💬 D05712 💬 Regramostim [1] 229 💬
25 Pathways in cancer 💬
[1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
26 Pathways in cancer 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
27 Pathways in cancer 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
28 PPAR signaling pathway 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
29 PPAR signaling pathway 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
30 Thermogenesis 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
31 Thermogenesis 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
32 Thyroid cancer 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
33 Thyroid cancer 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
34 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
35 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬