Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
2 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
3 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] PTH1R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
4 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
5 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
6 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
7 Mineral absorption 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
8 Mineral absorption 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
9 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00244 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
10 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00972 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
11 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01357 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
12 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01402 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
13 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01637 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
14 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02032 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
15 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02286 💬 Betamethasone [7]  2 , 28, 46, 83, 90, 96, 235 💬
16 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00292 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
17 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00975 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
18 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01510 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
19 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01615 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
20 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01632 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
21 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01948 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
22 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02174 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
23 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02591 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
24 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02592 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
26 Neuroactive ligand-receptor interaction 💬
 [2] PTH1R, PTH2R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
27 Parathyroid hormone synthesis, secretion and action 💬
 [1] PTH1R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
28 Parathyroid hormone synthesis, secretion and action 💬
 [1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
29 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
30 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
31 Tuberculosis 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
32 Tuberculosis 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬

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