Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Breast cancer 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
2 Calcium signaling pathway 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
3 Chemical carcinogenesis - receptor activation 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
4 Chemical carcinogenesis - receptor activation 💬
[1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬
5 Cytokine-cytokine receptor interaction 💬
[1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
6 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
7 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬
8 Gastric cancer 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
9 Growth hormone synthesis, secretion and action 💬
[1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
10 JAK-STAT signaling pathway 💬
[1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
11 MAPK signaling pathway 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
12 Melanoma 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
13 Mineral absorption 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
14 Mineral absorption 💬
[1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬
15 Neuroactive ligand-receptor interaction 💬
[1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
16 NOD-like receptor signaling pathway 💬
[1] CASR 💬 D03504 💬 Cinacalcet [2] 85, 238 💬
17 NOD-like receptor signaling pathway 💬
[1] CASR 💬 D03505 💬 Cinacalcet [2] 85, 238 💬
18 Parathyroid hormone synthesis, secretion and action 💬
[1] CASR 💬 D03504 💬 Cinacalcet [2] 85, 238 💬
19 Parathyroid hormone synthesis, secretion and action 💬
[1] CASR 💬 D03505 💬 Cinacalcet [2] 85, 238 💬
20 Parathyroid hormone synthesis, secretion and action 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
21 Parathyroid hormone synthesis, secretion and action 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
22 Parathyroid hormone synthesis, secretion and action 💬
[1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬
23 Pathways in cancer 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
24 PI3K-Akt signaling pathway 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
25 PI3K-Akt signaling pathway 💬
[1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
26 Rap1 signaling pathway 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
27 Ras signaling pathway 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
28 Regulation of actin cytoskeleton 💬
[1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
29 Tuberculosis 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
30 Tuberculosis 💬
[1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬