Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
2 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
3 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
4 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
5 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
6 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
7 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
8 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
ESR1 [2] ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
9 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
10 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
11 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
12 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
13 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [3] AR, ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
14 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F8 [1] F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
15 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F8 [1] F8 💬 |
D02235 D02235 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
16 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
17 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
18 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
19 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
20 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MPL [1] MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 [4] 60, 63, 64, 65 💬 |
21 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
22 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
23 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
24 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
25 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
26 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
27 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
28 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
29 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
MS4A1 [1] MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 006 [49] 6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
30 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
31 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
32 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
33 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
34 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
35 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
MPL [1] MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 [4] 60, 63, 64, 65 💬 |
36 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
37 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
38 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
39 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
40 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
41 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
42 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
43 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
44 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00975 D00975 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
45 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01510 D01510 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
46 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01615 D01615 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
47 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01632 D01632 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
48 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01948 D01948 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
49 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02174 D02174 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
50 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02591 D02591 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
51 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02592 D02592 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
52 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
53 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
54 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
55 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
56 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
57 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
58 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
59 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
60 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
61 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
62 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
63 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
64 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
65 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
66 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [48] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
67 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
68 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
AR [2] AR, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
69 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
70 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
71 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
72 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
73 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AR [2] AR, ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
74 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
75 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
76 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
77 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
78 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
79 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
80 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
81 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
82 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
83 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 36 drugs (DrugBank) and 40 diseases in DDrare |
PGR [1] PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
84 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
85 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
AR [1] AR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
86 | Proteasome 💬 Related to 2 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
87 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
88 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
89 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
90 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
91 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
92 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
93 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
94 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
95 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
96 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
97 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
98 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
99 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |