Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
2 Alcoholism 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
3 Alcoholism 💬
[2] DRD1, DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
4 Alcoholism 💬
[2] DRD1, DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
5 Alzheimer disease 💬
[1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
6 Amphetamine addiction 💬
[1] DRD1 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
7 Amphetamine addiction 💬
[1] DRD1 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
8 Amphetamine addiction 💬
[1] DRD1 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
9 Amphetamine addiction 💬
[1] DRD1 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
10 Axon guidance 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
11 Calcium signaling pathway 💬
[1] DRD1 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
12 Calcium signaling pathway 💬
[1] DRD1 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
13 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
14 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
15 cAMP signaling pathway 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
16 cAMP signaling pathway 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
17 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
18 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
19 cAMP signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
20 cGMP-PKG signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
21 Chemokine signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
22 Cocaine addiction 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
23 Cocaine addiction 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
24 Cocaine addiction 💬
[2] DRD1, DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
25 Cocaine addiction 💬
[2] DRD1, DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
26 Dopaminergic synapse 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
27 Dopaminergic synapse 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
28 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
29 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
30 Focal adhesion 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
31 Gap junction 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
32 Gap junction 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
33 Gap junction 💬
[2] DRD1, DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
34 Gap junction 💬
[2] DRD1, DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
35 Human cytomegalovirus infection 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
36 Insulin secretion 💬
[1] SNAP25 💬 D00783 💬 Botulinum toxin type A [13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
37 Leukocyte transendothelial migration 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
38 Lipid and atherosclerosis 💬
[1] ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
39 MAPK signaling pathway 💬
[1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
40 MicroRNAs in cancer 💬
[1] ROCK1 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
41 Morphine addiction 💬
[1] DRD1 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
42 Morphine addiction 💬
[1] DRD1 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
43 Morphine addiction 💬
[1] DRD1 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
44 Morphine addiction 💬
[1] DRD1 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
45 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
46 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
47 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
48 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
49 Oxytocin signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
50 Parkinson disease 💬
[2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
51 Parkinson disease 💬
[2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
52 Parkinson disease 💬
[2] DRD1, DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
53 Parkinson disease 💬
[2] DRD1, DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
54 Parkinson disease 💬
[1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
55 Pathogenic Escherichia coli infection 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
56 Pathways in cancer 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
57 Pathways of neurodegeneration - multiple diseases 💬
[1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
58 Platelet activation 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
59 Proteoglycans in cancer 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
60 Rap1 signaling pathway 💬
[1] DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
61 Rap1 signaling pathway 💬
[1] DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
62 Rap1 signaling pathway 💬
[1] DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
63 Rap1 signaling pathway 💬
[1] DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
64 Regulation of actin cytoskeleton 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
65 Salmonella infection 💬
[1] ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
66 Shigellosis 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
67 Sphingolipid signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
68 Synaptic vesicle cycle 💬
[1] SNAP25 💬 D00783 💬 Botulinum toxin type A [13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
69 TGF-beta signaling pathway 💬
[1] ROCK1 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
70 Tight junction 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
71 Vascular smooth muscle contraction 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
72 Wnt signaling pathway 💬
[1] ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
73 Yersinia infection 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬