Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
2 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
3 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
5 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
6 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
7 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
8 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
9 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
10 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
11 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
12 | Bladder cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 23 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
13 | Bladder cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 23 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
14 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
15 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
16 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
17 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
18 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
19 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
20 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
21 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
22 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
23 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
24 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
25 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
26 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
27 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
28 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
29 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
SSTR1 [3] SSTR1, SSTR2, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
30 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
31 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
32 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
33 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
34 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
35 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
36 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
37 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
38 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
39 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
40 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
41 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
42 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
43 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
44 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
45 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
46 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
47 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
48 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
49 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
50 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
51 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
52 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
53 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
54 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
55 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
56 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
57 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
58 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
59 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
60 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
61 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
62 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
63 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
64 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
65 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
66 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
67 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
68 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
69 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
70 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
71 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
72 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
73 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
74 | Endometrial cancer 💬 Related to 10 target genes, 15 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
75 | Endometrial cancer 💬 Related to 10 target genes, 15 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
76 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 16 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
77 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 16 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
78 | ErbB signaling pathway 💬 Related to 12 target genes, 22 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
79 | ErbB signaling pathway 💬 Related to 12 target genes, 22 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
80 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
81 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
82 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
83 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
84 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
85 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
86 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
87 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
88 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
89 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
90 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
91 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
92 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
93 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
94 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
95 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
96 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
97 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
98 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
99 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
100 | Glioma 💬 Related to 14 target genes, 26 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
101 | Glioma 💬 Related to 14 target genes, 26 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
102 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
103 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
104 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
105 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
106 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
107 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
SSTR1 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
108 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
109 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
110 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
111 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
112 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
113 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
114 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
115 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
116 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
117 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
118 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
119 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
120 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
121 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
PRL [1] PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
122 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
PRL [1] PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
123 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
PRL [1] PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
124 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
125 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
126 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
127 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
128 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
129 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
130 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
131 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
132 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
133 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
134 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
135 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
136 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 [2] DRD2, PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
137 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 [2] DRD2, PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
138 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 [2] DRD2, PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
139 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
140 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
141 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00975 D00975 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
142 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01510 D01510 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
143 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01615 D01615 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
144 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01632 D01632 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
145 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01948 D01948 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
146 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02174 D02174 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
147 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02591 D02591 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
148 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02592 D02592 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
149 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
SSTR1 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
150 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
151 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
152 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
153 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
154 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
155 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
156 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
157 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
158 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
159 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
160 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
161 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
162 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
163 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
164 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
165 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
166 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
167 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
168 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
169 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
170 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
171 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
172 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
173 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
174 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
175 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
176 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL [1] PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
177 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL [1] PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
178 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL [1] PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
179 | Platinum drug resistance 💬 Related to 9 target genes, 13 drugs (DrugBank) and 22 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
180 | Platinum drug resistance 💬 Related to 9 target genes, 13 drugs (DrugBank) and 22 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
181 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
182 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
183 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
PRL [1] PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
184 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
PRL [1] PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
185 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
PRL [1] PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
186 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
187 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
188 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
189 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
190 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
191 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
192 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
193 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
194 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
195 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
196 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
197 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
198 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
199 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
200 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
201 | Ras signaling pathway 💬 Related to 35 target genes, 49 drugs (DrugBank) and 61 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
202 | Ras signaling pathway 💬 Related to 35 target genes, 49 drugs (DrugBank) and 61 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
203 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
204 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
205 | Relaxin signaling pathway 💬 Related to 19 target genes, 27 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
206 | Relaxin signaling pathway 💬 Related to 19 target genes, 27 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
207 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
208 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
209 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
210 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
211 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
212 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ERBB2 [1] ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |