Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Acute myeloid leukemia 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
4 Axon guidance 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5 Axon guidance 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6 Bladder cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
7 Breast cancer 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
8 Breast cancer 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
9 Calcium signaling pathway 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
10 Calcium signaling pathway 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
11 Calcium signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
12 Cell cycle 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
13 Cell cycle 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
14 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
15 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
16 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
17 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
18 Chemical carcinogenesis - reactive oxygen species 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
19 Chemical carcinogenesis - receptor activation 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
20 Choline metabolism in cancer 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
21 Choline metabolism in cancer 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
22 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
23 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
24 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
25 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26 EGFR tyrosine kinase inhibitor resistance 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
27 Endocytosis 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
28 Endocytosis 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
29 ErbB signaling pathway 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
30 ErbB signaling pathway 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
31 Fluid shear stress and atherosclerosis 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
32 Focal adhesion 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
33 Focal adhesion 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
34 Focal adhesion 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
35 Gap junction 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
36 Gap junction 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
37 Glioma 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
38 Glioma 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
39 Hematopoietic cell lineage 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
40 Hematopoietic cell lineage 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
41 HIF-1 signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
42 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
43 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
44 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
45 Human papillomavirus infection 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
46 JAK-STAT signaling pathway 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
47 JAK-STAT signaling pathway 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
48 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
49 MAPK signaling pathway 💬
 [2] KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
50 MAPK signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
51 MAPK signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
52 Melanogenesis 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
53 Melanogenesis 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
54 Melanoma 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
55 Melanoma 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
56 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
57 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
58 MicroRNAs in cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
59 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
60 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
61 Pancreatic cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
62 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
63 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
64 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
65 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
66 Pathways in cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
67 Phospholipase D signaling pathway 💬
 [2] KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
68 Phospholipase D signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
69 PI3K-Akt signaling pathway 💬
 [2] KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
70 PI3K-Akt signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
71 PI3K-Akt signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
72 Prostate cancer 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
73 Prostate cancer 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
74 Proteoglycans in cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
75 Rap1 signaling pathway 💬
 [2] KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
76 Rap1 signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
77 Rap1 signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
78 Ras signaling pathway 💬
 [3] ABL1, KIT, PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
79 Ras signaling pathway 💬
 [3] ABL1, KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
80 Ras signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
81 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
82 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
83 Relaxin signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
84 Renal cell carcinoma 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
85 Rheumatoid arthritis 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
86 VEGF signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
87 Viral myocarditis 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
88 Viral myocarditis 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

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