Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Biosynthesis of cofactors 💬
[2] NQO1, VKORC1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
2 Biosynthesis of cofactors 💬
[2] NQO1, VKORC1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
3 Biosynthesis of cofactors 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
4 Chemical carcinogenesis - reactive oxygen species 💬
[1] NQO1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
5 Chemical carcinogenesis - reactive oxygen species 💬
[1] NQO1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
6 Chemical carcinogenesis - reactive oxygen species 💬
[1] NQO1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
7 Complement and coagulation cascades 💬
[1] F10 💬 D07086 💬 Rivaroxaban [5] 46, 49, 75, 91, 210 💬
8 Complement and coagulation cascades 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
9 Coronavirus disease - COVID-19 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
10 Fluid shear stress and atherosclerosis 💬
[1] NQO1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
11 Fluid shear stress and atherosclerosis 💬
[1] NQO1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
12 Fluid shear stress and atherosclerosis 💬
[1] NQO1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
13 Hepatocellular carcinoma 💬
[1] NQO1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
14 Hepatocellular carcinoma 💬
[1] NQO1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
15 Hepatocellular carcinoma 💬
[1] NQO1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
16 Metabolic pathways 💬
[2] NQO1, VKORC1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
17 Metabolic pathways 💬
[2] NQO1, VKORC1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
18 Metabolic pathways 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
19 Neuroactive ligand-receptor interaction 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
20 Pathogenic Escherichia coli infection 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
21 Pathways in cancer 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
22 Pathways in cancer 💬
[1] NQO1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
23 Pathways in cancer 💬
[1] NQO1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
24 Pathways in cancer 💬
[1] NQO1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
25 Phospholipase D signaling pathway 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
26 Platelet activation 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
27 Regulation of actin cytoskeleton 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
28 Ubiquinone and other terpenoid-quinone biosynthesis 💬
[2] NQO1, VKORC1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
29 Ubiquinone and other terpenoid-quinone biosynthesis 💬
[2] NQO1, VKORC1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
30 Ubiquinone and other terpenoid-quinone biosynthesis 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬