Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Prostate cancer 💬
[1] AR 💬 D03338 💬 Calusterone [3]  2 , 46, 71 💬
2 Prostate cancer 💬
[1] AR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
3 Prostate cancer 💬
[1] AR 💬 D00586 💬 Flutamide [1] 81 💬
4 Prostate cancer 💬
[1] AR 💬 D08250 💬 Nandrolone [2] 60, 85 💬
5 Prostate cancer 💬
[1] AR 💬 D00955 💬 Nandrolone decanoate [2] 60, 85 💬
6 Prostate cancer 💬
[1] AR 💬 D00462 💬 Oxandrolone [2] 211, 285 💬
7 Prostate cancer 💬
[1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
8 Prostate cancer 💬
[1] AR 💬 D00444 💬 Stanozolol [1] 60 💬
9 Prostate cancer 💬
[1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
10 Prostate cancer 💬
[1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
11 Prostate cancer 💬
[1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
12 Prostate cancer 💬
[1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
13 Prostate cancer 💬
[1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
14 Prostate cancer 💬
[1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
15 Prostate cancer 💬
[1] AR 💬 D08573 💬 Testosterone decanoate [1] 113 💬
16 Prostate cancer 💬
[1] AR 💬 D00958 💬 Testosterone enanthate [2] 13, 113 💬
17 Prostate cancer 💬
[1] AR 💬 D08574 💬 Testosterone phenylpropionate [1] 113 💬
18 Prostate cancer 💬
[1] AR 💬 D00959 💬 Testosterone propionate [1] 113 💬
19 Prostate cancer 💬
[1] AR 💬 D06087 💬 Testosterone undecanoate [2] 13, 60 💬
20 Prostate cancer 💬
[1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
21 Prostate cancer 💬
[1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
22 Prostate cancer 💬
[3] BRAF, PDGFRB, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
23 Prostate cancer 💬
[3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
24 Prostate cancer 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
25 Prostate cancer 💬
[1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
26 Prostate cancer 💬
[1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
27 Prostate cancer 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
28 Prostate cancer 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
29 Prostate cancer 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
30 Prostate cancer 💬
[2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
31 Prostate cancer 💬
[2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
32 Prostate cancer 💬
[2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
33 Prostate cancer 💬
[2] FGFR1, FGFR2 💬 D11589 💬 Infigratinib [1] 276 💬
34 Prostate cancer 💬
[4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
35 Prostate cancer 💬
[1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
36 Prostate cancer 💬
[1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
37 Prostate cancer 💬
[1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
38 Prostate cancer 💬
[1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
39 Prostate cancer 💬
[1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
40 Prostate cancer 💬
[1] IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
41 Prostate cancer 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
42 Prostate cancer 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
43 Prostate cancer 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
44 Prostate cancer 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
45 Prostate cancer 💬
[1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
46 Prostate cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
47 Prostate cancer 💬
[1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
48 Prostate cancer 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
49 Prostate cancer 💬
[1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
50 Prostate cancer 💬
[1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
51 Prostate cancer 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
52 Prostate cancer 💬
[2] PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib [2] 28, 34 💬
53 Prostate cancer 💬
[2] PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
54 Prostate cancer 💬
[1] PDGFRB 💬 D03658 💬 Dasatinib [2] 51, 85 💬
55 Prostate cancer 💬
[1] PDGFRB 💬 D06414 💬 Dasatinib [2] 51, 85 💬
56 Prostate cancer 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
57 Prostate cancer 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
58 Prostate cancer 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
59 Prostate cancer 💬
[1] SRD5A2 💬 D03820 💬 Dutasteride [2]  1 ,  2  💬
60 Prostate cancer 💬
[1] SRD5A2 💬 D00321 💬 Finasteride [1]  6  💬