Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chemokine signaling pathway 💬
[1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Chemokine signaling pathway 💬
[2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
3 Chemokine signaling pathway 💬
[2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 Chemokine signaling pathway 💬
[1] CCL2 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
5 Chemokine signaling pathway 💬
[2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
6 Chemokine signaling pathway 💬
[1] CCR4 💬 D09761 💬 Mogamulizumab [1] 26 💬
7 Chemokine signaling pathway 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
8 Chemokine signaling pathway 💬
[2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
9 Chemokine signaling pathway 💬
[1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
10 Chemokine signaling pathway 💬
[1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
11 Chemokine signaling pathway 💬
[1] JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
12 Chemokine signaling pathway 💬
[2] JAK2, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
13 Chemokine signaling pathway 💬
[2] JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
14 Chemokine signaling pathway 💬
[1] MAP2K1 💬 D10604 💬 Binimetinib [1] 34 💬
15 Chemokine signaling pathway 💬
[1] MAP2K1 💬 D10405 💬 Cobimetinib [1] 280 💬
16 Chemokine signaling pathway 💬
[1] MAP2K1 💬 D09666 💬 Selumetinib [1] 34 💬
17 Chemokine signaling pathway 💬
[1] MAP2K1 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
18 Chemokine signaling pathway 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
19 Chemokine signaling pathway 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
20 Chemokine signaling pathway 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
21 Chemokine signaling pathway 💬
[1] PRKCD 💬 D09671 💬 Sotrastaurin [1] 97 💬
22 Chemokine signaling pathway 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
23 Chemokine signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
24 Chemokine signaling pathway 💬
[1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬
25 Chemokine signaling pathway 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
26 Chemokine signaling pathway 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
27 Chemokine signaling pathway 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
28 Chemokine signaling pathway 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬