Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Endocytosis 💬
[1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
2 Endocytosis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
3 Endocytosis 💬
[2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
4 Endocytosis 💬
[1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
5 Endocytosis 💬
[1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
6 Endocytosis 💬
[1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
7 Endocytosis 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
8 Endocytosis 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
9 Endocytosis 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
10 Endocytosis 💬
[1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
11 Endocytosis 💬
[1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
12 Endocytosis 💬
[1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
13 Endocytosis 💬
[1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
14 Endocytosis 💬
[2] FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
15 Endocytosis 💬
[3] FGFR2, FGFR3, PDGFRA 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
16 Endocytosis 💬
[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
17 Endocytosis 💬
[1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
18 Endocytosis 💬
[1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
19 Endocytosis 💬
[1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
20 Endocytosis 💬
[1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
21 Endocytosis 💬
[1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
22 Endocytosis 💬
[1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
23 Endocytosis 💬
[3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
24 Endocytosis 💬
[1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
25 Endocytosis 💬
[1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26 Endocytosis 💬
[1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
27 Endocytosis 💬
[1] PDGFRA 💬 D06402 💬 Sunitinib [2] 28, 34 💬
28 Endocytosis 💬
[1] PDGFRA 💬 D08552 💬 Sunitinib [2] 28, 34 💬
29 Endocytosis 💬
[1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
30 Endocytosis 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
31 Endocytosis 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
32 Endocytosis 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
33 Endocytosis 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
34 Endocytosis 💬
[1] TFRC 💬 D11812 💬 Pabinafusp alfa [1] 19 💬