Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Signaling pathways regulating pluripotency of stem cells 💬
 [1] ACVR2A 💬 D09670 💬 Sotatercept [2] 86, 284 💬
2 Signaling pathways regulating pluripotency of stem cells 💬
 [2] ACVR2A, ACVR2B 💬 D10620 💬 Bimagrumab [1] 15 💬
3 Signaling pathways regulating pluripotency of stem cells 💬
 [1] BMPR2 💬 D03779 💬 Dibotermin alfa [1] 34 💬
4 Signaling pathways regulating pluripotency of stem cells 💬
 [3] FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
5 Signaling pathways regulating pluripotency of stem cells 💬
 [3] FGFR1, FGFR2, FGFR3 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
6 Signaling pathways regulating pluripotency of stem cells 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
7 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
8 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
9 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
10 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
11 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
12 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
13 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
14 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
15 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
16 Signaling pathways regulating pluripotency of stem cells 💬
 [3] JAK1, JAK2, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
17 Signaling pathways regulating pluripotency of stem cells 💬
 [3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
18 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
19 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
20 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
21 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
22 Signaling pathways regulating pluripotency of stem cells 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
23 Signaling pathways regulating pluripotency of stem cells 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
24 Signaling pathways regulating pluripotency of stem cells 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
25 Signaling pathways regulating pluripotency of stem cells 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
26 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
27 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬