Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Renin-angiotensin system 💬
[1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
2 Renin-angiotensin system 💬
[1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
3 Renin-angiotensin system 💬
[1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
4 Renin-angiotensin system 💬
[1] ACE 💬 D01069 💬 Cilazapril [1] 66 💬
5 Renin-angiotensin system 💬
[1] ACE 💬 D07699 💬 Cilazapril [1] 66 💬
6 Renin-angiotensin system 💬
[1] ACE 💬 D00621 💬 Enalapril [6] 19, 46, 66, 113, 210, 222 💬
7 Renin-angiotensin system 💬
[1] ACE 💬 D07892 💬 Enalapril [6] 19, 46, 66, 113, 210, 222 💬
8 Renin-angiotensin system 💬
[1] ACE 💬 D08068 💬 Imidapril [1] 67 💬
9 Renin-angiotensin system 💬
[1] ACE 💬 D00362 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
10 Renin-angiotensin system 💬
[1] ACE 💬 D08131 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
11 Renin-angiotensin system 💬
[1] ACE 💬 D00623 💬 Moexipril [1] 93 💬
12 Renin-angiotensin system 💬
[1] ACE 💬 D08225 💬 Moexipril [1] 93 💬
13 Renin-angiotensin system 💬
[1] ACE 💬 D00624 💬 Perindopril [4] 58, 113, 167, 222 💬
14 Renin-angiotensin system 💬
[1] ACE 💬 D03753 💬 Perindopril [4] 58, 113, 167, 222 💬
15 Renin-angiotensin system 💬
[1] ACE 💬 D00459 💬 Quinapril [1] 19 💬
16 Renin-angiotensin system 💬
[1] ACE 💬 D03752 💬 Quinapril [1] 19 💬
17 Renin-angiotensin system 💬
[1] ACE 💬 D00421 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
18 Renin-angiotensin system 💬
[1] AGTR1 💬 D00522 💬 Candesartan [2] 58, 67 💬
19 Renin-angiotensin system 💬
[1] AGTR1 💬 D00522 💬 Candesartan cilexetil [1] 67 💬
20 Renin-angiotensin system 💬
[1] AGTR1 💬 D00626 💬 Candesartan cilexetil [1] 67 💬
21 Renin-angiotensin system 💬
[1] AGTR1 💬 D00523 💬 Irbesartan [4] 66, 167, 168, 222 💬
22 Renin-angiotensin system 💬
[1] AGTR1 💬 D00357 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
23 Renin-angiotensin system 💬
[1] AGTR1 💬 D08146 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
24 Renin-angiotensin system 💬
[1] AGTR1 💬 D11776 💬 Sparsentan [3] 66, 218, 222 💬
25 Renin-angiotensin system 💬
[1] AGTR1 💬 D00627 💬 Telmisartan [2] 66, 67 💬
26 Renin-angiotensin system 💬
[1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
27 Renin-angiotensin system 💬
[2] AGTR1, AGTR2 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
28 Renin-angiotensin system 💬
[2] AGTR1, AGTR2 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
29 Renin-angiotensin system 💬
[1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
30 Renin-angiotensin system 💬
[1] MME 💬 D10225 💬 Sacubitril [1] 58 💬
31 Renin-angiotensin system 💬
[1] REN 💬 D03208 💬 Aliskiren [3] 66, 167, 222 💬