Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Fc epsilon RI signaling pathway 💬
 [1] ALOX5 💬 D01773 💬 Oxatomide [1] 113 💬
2 Fc epsilon RI signaling pathway 💬
 [1] ALOX5 💬 D00414 💬 Zileuton [3] 85, 160, 164 💬
3 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D10893 💬 Acalabrutinib [2] 46, 61 💬
4 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
5 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D11457 💬 Fenebrutinib [1] 13 💬
6 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
7 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D12160 💬 Orelabrutinib [3] 13, 61, 63 💬
8 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D11422 💬 Zanubrutinib [2] 300, 331 💬
9 Fc epsilon RI signaling pathway 💬
 [1] CSF2 💬 D11343 💬 Otilimab [2] 46, 256 💬
10 Fc epsilon RI signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
11 Fc epsilon RI signaling pathway 💬
 [1] FYN 💬 D03658 💬 Dasatinib [2] 51, 85 💬
12 Fc epsilon RI signaling pathway 💬
 [1] FYN 💬 D06414 💬 Dasatinib [2] 51, 85 💬
13 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 D08857 💬 Anrukinzumab [1] 97 💬
14 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 D09633 💬 Lebrikizumab [1] 85 💬
15 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 D09979 💬 Tralokinumab [2] 85, 97 💬
16 Fc epsilon RI signaling pathway 💬
 [1] IL4 💬 D03117 💬 Binetrakin [1] 46 💬
17 Fc epsilon RI signaling pathway 💬
 [1] IL5 💬 D04923 💬 Mepolizumab [4] 44, 45, 98, 162 💬
18 Fc epsilon RI signaling pathway 💬
 [1] IL5 💬 D08985 💬 Reslizumab [2] 44, 98 💬
19 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
20 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
21 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
22 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
23 Fc epsilon RI signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
24 Fc epsilon RI signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
25 Fc epsilon RI signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
26 Fc epsilon RI signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
27 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
28 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
29 Fc epsilon RI signaling pathway 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
30 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
31 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
32 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
33 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
34 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
35 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
36 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
37 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
38 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
39 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
40 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬