Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Relaxin signaling pathway 💬
[1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2 Relaxin signaling pathway 💬
[1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3 Relaxin signaling pathway 💬
[1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
4 Relaxin signaling pathway 💬
[1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
5 Relaxin signaling pathway 💬
[1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
6 Relaxin signaling pathway 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
7 Relaxin signaling pathway 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
8 Relaxin signaling pathway 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
9 Relaxin signaling pathway 💬
[1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
10 Relaxin signaling pathway 💬
[1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
11 Relaxin signaling pathway 💬
[1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
12 Relaxin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
13 Relaxin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
14 Relaxin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
15 Relaxin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
16 Relaxin signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
17 Relaxin signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
18 Relaxin signaling pathway 💬
[1] MMP13 💬 D08859 💬 Apratastat [1] 46 💬
19 Relaxin signaling pathway 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
20 Relaxin signaling pathway 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
21 Relaxin signaling pathway 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
22 Relaxin signaling pathway 💬
[1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
23 Relaxin signaling pathway 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
24 Relaxin signaling pathway 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
25 Relaxin signaling pathway 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
26 Relaxin signaling pathway 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
27 Relaxin signaling pathway 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
28 Relaxin signaling pathway 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
29 Relaxin signaling pathway 💬
[1] TGFB1 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
30 Relaxin signaling pathway 💬
[1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
31 Relaxin signaling pathway 💬
[1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬
32 Relaxin signaling pathway 💬
[2] VEGFA, VEGFB 💬 D09574 💬 Aflibercept [2] 90, 166 💬