Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Amoebiasis 💬
[1] CSF2 💬 D11343 💬 Otilimab [2] 46, 256 💬
2 Amoebiasis 💬
[1] IFNG 💬 D11120 💬 Emapalumab [2] 49, 107 💬
3 Amoebiasis 💬
[1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
4 Amoebiasis 💬
[4] IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
5 Amoebiasis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
6 Amoebiasis 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
7 Amoebiasis 💬
[1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
8 Amoebiasis 💬
[1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
9 Amoebiasis 💬
[2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
10 Amoebiasis 💬
[1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
11 Amoebiasis 💬
[1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
12 Amoebiasis 💬
[2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
13 Amoebiasis 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
14 Amoebiasis 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
15 Amoebiasis 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
16 Amoebiasis 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
17 Amoebiasis 💬
[3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
18 Amoebiasis 💬
[1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
19 Amoebiasis 💬
[1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
20 Amoebiasis 💬
[1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
21 Amoebiasis 💬
[1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
22 Amoebiasis 💬
[1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
23 Amoebiasis 💬
[1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
24 Amoebiasis 💬
[1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
25 Amoebiasis 💬
[1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
26 Amoebiasis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬