Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Acute myeloid leukemia 💬
 [4] BRAF, FLT3, KIT, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
3 Acute myeloid leukemia 💬
 [4] BRAF, FLT3, KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 Acute myeloid leukemia 💬
 [3] CSF1R, FLT3, KIT 💬 D11270 💬 Pexidartinib [1] 34 💬
5 Acute myeloid leukemia 💬
 [1] CSF2 💬 D11343 💬 Otilimab [2] 46, 256 💬
6 Acute myeloid leukemia 💬
 [2] FLT3, KIT 💬 D06402 💬 Sunitinib [2] 28, 34 💬
7 Acute myeloid leukemia 💬
 [2] FLT3, KIT 💬 D08552 💬 Sunitinib [2] 28, 34 💬
8 Acute myeloid leukemia 💬
 [1] KIT 💬 D03658 💬 Dasatinib [2] 51, 85 💬
9 Acute myeloid leukemia 💬
 [1] KIT 💬 D06414 💬 Dasatinib [2] 51, 85 💬
10 Acute myeloid leukemia 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
11 Acute myeloid leukemia 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
12 Acute myeloid leukemia 💬
 [1] KIT 💬 D10229 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
13 Acute myeloid leukemia 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
14 Acute myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
15 Acute myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
16 Acute myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
17 Acute myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
18 Acute myeloid leukemia 💬
 [1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
19 Acute myeloid leukemia 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
20 Acute myeloid leukemia 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
21 Acute myeloid leukemia 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
22 Acute myeloid leukemia 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
23 Acute myeloid leukemia 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
24 Acute myeloid leukemia 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
25 Acute myeloid leukemia 💬
 [2] PML, RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
26 Acute myeloid leukemia 💬
 [1] RARA 💬 D02754 💬 Acitretin [1] 37 💬
27 Acute myeloid leukemia 💬
 [1] RARA 💬 D02815 💬 Alitretinoin [1] 49 💬
28 Acute myeloid leukemia 💬
 [1] RARA 💬 D04162 💬 Fenretinide [1] 299 💬
29 Acute myeloid leukemia 💬
 [1] RARA 💬 D00348 💬 Isotretinoin [4] 36, 39, 159, 160 💬
30 Acute myeloid leukemia 💬
 [1] RARA 💬 D01418 💬 Tamibarotene [2] 26, 96 💬
31 Acute myeloid leukemia 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
32 Acute myeloid leukemia 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬