Drug Description in Trials / DrugBank / KEGG DRUG

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No.

薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

1

(RS)-baclofen
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 10 💬

2

(RS)-baclofen, naltrexone hydrochloride and D-sorbitol
(Kemstro (TN))

3件: Baclofen (Kemstro),
Naltrexone,
Sorbitol

3件: Sorbitol solution ,
Baclofen (Kemstro (TN)),
Naltrexone 💬

Name	Other Names
Sorbitol solution	Sorbitol solution (USP) D-Sorbitol (JP18) Sorbitol (NF) Sorbitol 3% in plastic container (TN) D-ソルビトールソルビトール D−ソルビトールウロマチック
Baclofen	Baclofen (JP18/USP/INN) Kemstro (TN) Lioresal (TN) FLEQSUVY GABLOFEN LYVISPAH OZOBAX バクロフェンギャバロンリオレサール
Naltrexone	Naltrexone (USAN/INN) Vivitrol (TN) ナルトレキソン

5件: GABBR1,
GABBR2,
OPRD1,
OPRK1,
OPRM1 💬

Name	Full Name
GABBR1	gamma-aminobutyric acid type B receptor subunit 1
GABBR2	gamma-aminobutyric acid type B receptor subunit 2
OPRD1	opioid receptor delta 1
OPRK1	opioid receptor kappa 1
OPRM1	opioid receptor mu 1

9件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

1件: 10 💬

3

AERT, (R)-Baclofen
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

4

BACLOFEN
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

8件: 2, 10, 13, 18, 65, 70, 149, 206 💬

告示番号	日本語名	英語名
2	筋萎縮性側索硬化症	Amyotrophic lateral sclerosis
10	シャルコー・マリー・トゥース病	Charcot-Marie-Tooth disease
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
18	脊髄小脳変性症（多系統萎縮症を除く。）	Spinocerebellar degeneration
65	原発性免疫不全症候群	Primary immunodeficiency
70	広範脊柱管狭窄症	Spinal stenosis
149	片側痙攣・片麻痺・てんかん症候群	Hemiconvulsion hemiplegia epilepsy syndrome
206	脆弱Ｘ症候群	Fragile X syndrome

5

Baclofen (baclofen Tab. 10mg) treatment
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 70 💬

6

Baclofen 20 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

7

Baclofen ER Capsules (GRS) 10 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

8

Baclofen ER Capsules (GRS) 20 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

9

Baclofen ER Capsules (GRS) 30mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

10

Baclofen ER Capsules (GRS) 40mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

11

Baclofen ER Capsules (GRS) 50 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

12

Baclofen IR
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

13

Baclofen Tablets USP
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

14

Baclofen Tablets USP 10 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

15

Encapsulated Baclofen 20 mg
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 13 💬

16

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-

-

1件: 13 💬

17

RS-BACLOFEN
(Kemstro (TN))

1件: Baclofen (Kemstro)

1件: Baclofen (Kemstro (TN)) 💬

2件: GABBR1,
GABBR2 💬

7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬

1件: 10 💬