Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Elexacaftor / Ivacaftor / Tezacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
2Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
3Elexacaftor-tezacaftor-ivacaftor exposure3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
4Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
5Ivacaftor or elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
6TEZACAFTOR1件: Tezacaftor1件: Tezacaftor 💬1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
7Tezacaftor (TEZ)1件: Tezacaftor1件: Tezacaftor 💬1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
8Tezacaftor/Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
9Tezacaftor/Ivacaftor + Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
10Tezacaftor/Ivacaftor 100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
11Tezacaftor/Ivacaftor/100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
12Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor4件: Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		4件: Ivacaftor ,
Lumacaftor ,
Tezacaftor ,
Elexacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
13VX-121/tezacaftor/deutivacaftor2件: Deutivacaftor,
Tezacaftor		2件: Tezacaftor ,
Deutivacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
14VX-659/Tezacaftor/Ivacaftor3件: Ivacaftor,
Tezacaftor,
VX-659		2件: Ivacaftor ,
Tezacaftor 💬		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬