Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Tight junction 💬
1件: CACNA1D 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Tight junction 💬
1件: CACNA1D 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
3 Tight junction 💬
1件: CACNA1D 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
4 Tight junction 💬
1件: CACNA1D 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Tight junction 💬
1件: CACNA1D 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
6 Tight junction 💬
1件: CACNA1D 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
7 Tight junction 💬
1件: CACNA1D 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
8 Tight junction 💬
1件: CACNA1D 💬 D00349 💬 Isradipine 1件:  6  💬
9 Tight junction 💬
1件: CACNA1D 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
10 Tight junction 💬
1件: CACNA1D 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
11 Tight junction 💬
1件: CACNA1D 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
12 Tight junction 💬
1件: CACNA1D 💬 D01908 💬 Nilvadipine 1件: 90 💬
13 Tight junction 💬
1件: CACNA1D 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
14 Tight junction 💬
1件: CACNA1D 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
15 Tight junction 💬
1件: CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
16 Tight junction 💬
1件: CACNA1D 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
17 Tight junction 💬
1件: CACNA1D 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
18 Tight junction 💬
1件: CACNA1D 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
19 Tight junction 💬
1件: CDK4 💬 D10688 💬 Abemaciclib 1件: 34 💬
20 Tight junction 💬
1件: CFTR 💬 D11423 💬 Deutivacaftor 1件: 299 💬
21 Tight junction 💬
1件: CFTR 💬 D11507 💬 Elexacaftor 1件: 299 💬
22 Tight junction 💬
1件: CFTR 💬 D11724 💬 Galicaftor 1件: 299 💬
23 Tight junction 💬
1件: CFTR 💬 D09916 💬 Ivacaftor 1件: 299 💬
24 Tight junction 💬
1件: CFTR 💬 D10134 💬 Lumacaftor 1件: 299 💬
25 Tight junction 💬
1件: CFTR 💬 D11041 💬 Tezacaftor 1件: 299 💬
26 Tight junction 💬
1件: ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
27 Tight junction 💬
1件: ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
28 Tight junction 💬
1件: ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
29 Tight junction 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
30 Tight junction 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
31 Tight junction 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
32 Tight junction 💬
1件: PRKCE 💬 D09671 💬 Sotrastaurin 1件: 97 💬
33 Tight junction 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
34 Tight junction 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
35 Tight junction 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
36 Tight junction 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
37 Tight junction 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
38 Tight junction 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬