Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Gastric acid secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin 1件: 299 💬
2 Gastric acid secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin 3件:  8 , 46, 210 💬
3 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D08903 💬 Dexlansoprazole 1件: 98 💬
4 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D01984 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
5 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D04056 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
6 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D07917 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
7 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D09339 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
8 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D00355 💬 Lansoprazole 7件: 63, 71, 85, 98, 166, 222, 299 💬
9 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D00455 💬 Omeprazole 16件:  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
10 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D01207 💬 Omeprazole 16件:  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
11 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D05259 💬 Omeprazole 16件:  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
12 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D05261 💬 Omeprazole 16件:  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
13 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D02593 💬 Pantoprazole 2件: 13, 65 💬
14 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D05353 💬 Pantoprazole 2件: 13, 65 💬
15 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D00724 💬 Rabeprazole 2件:  2 , 51 💬
16 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D08463 💬 Rabeprazole 2件:  2 , 51 💬
17 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 D11784 💬 Vonoprazan 2件: 63, 98 💬
18 Gastric acid secretion 💬
1件: CA2 💬 D00218 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
19 Gastric acid secretion 💬
1件: CA2 💬 D01196 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
20 Gastric acid secretion 💬
1件: CA2 💬 D00518 💬 Diclofenamide 1件: 114 💬
21 Gastric acid secretion 💬
1件: CA2 💬 D00653 💬 Dorzolamide 1件: 90 💬
22 Gastric acid secretion 💬
1件: CA2 💬 D07871 💬 Dorzolamide 1件: 90 💬
23 Gastric acid secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
24 Gastric acid secretion 💬
1件: CFTR 💬 D11423 💬 Deutivacaftor 1件: 299 💬
25 Gastric acid secretion 💬
1件: CFTR 💬 D11507 💬 Elexacaftor 1件: 299 💬
26 Gastric acid secretion 💬
1件: CFTR 💬 D11724 💬 Galicaftor 1件: 299 💬
27 Gastric acid secretion 💬
1件: CFTR 💬 D09916 💬 Ivacaftor 1件: 299 💬
28 Gastric acid secretion 💬
1件: CFTR 💬 D10134 💬 Lumacaftor 1件: 299 💬
29 Gastric acid secretion 💬
1件: CFTR 💬 D11041 💬 Tezacaftor 1件: 299 💬
30 Gastric acid secretion 💬
1件: CHRM3 💬 D00113 💬 Atropine 2件:  2 , 299 💬
31 Gastric acid secretion 💬
1件: CHRM3 💬 D01077 💬 Atropine 2件:  2 , 299 💬
32 Gastric acid secretion 💬
1件: CHRM3 💬 D02069 💬 Atropine 2件:  2 , 299 💬
33 Gastric acid secretion 💬
1件: CHRM3 💬 D03011 💬 Atropine 2件:  2 , 299 💬
34 Gastric acid secretion 💬
1件: CHRM3 💬 D03814 💬 Atropine 2件:  2 , 299 💬
35 Gastric acid secretion 💬
1件: CHRM3 💬 D01000 💬 Bethanechol 1件: 98 💬
36 Gastric acid secretion 💬
1件: CHRM3 💬 D11383 💬 Blarcamesine 1件: 156 💬
37 Gastric acid secretion 💬
1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
38 Gastric acid secretion 💬
1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
39 Gastric acid secretion 💬
1件: CHRM3 💬 D00270 💬 Chlorpromazine 1件: 254 💬
40 Gastric acid secretion 💬
1件: CHRM3 💬 D00789 💬 Chlorpromazine 1件: 254 💬
41 Gastric acid secretion 💬
1件: CHRM3 💬 D03274 💬 Chlorpromazine 1件: 254 💬
42 Gastric acid secretion 💬
1件: CHRM3 💬 D04034 💬 Chlorpromazine 1件: 254 💬
43 Gastric acid secretion 💬
1件: CHRM3 💬 D01699 💬 Darifenacin 2件:  6 , 13 💬
44 Gastric acid secretion 💬
1件: CHRM3 💬 D03654 💬 Darifenacin 2件:  6 , 13 💬
45 Gastric acid secretion 💬
1件: CHRM3 💬 D07226 💬 Fesoterodine 1件:  6  💬
46 Gastric acid secretion 💬
1件: CHRM3 💬 D02212 💬 Ipratropium 2件:  6 , 86 💬
47 Gastric acid secretion 💬
1件: CHRM3 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
48 Gastric acid secretion 💬
1件: CHRM3 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
49 Gastric acid secretion 💬
1件: CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
50 Gastric acid secretion 💬
1件: CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
51 Gastric acid secretion 💬
1件: CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
52 Gastric acid secretion 💬
1件: CHRM3 💬 D00481 💬 Propantheline 1件: 26 💬
53 Gastric acid secretion 💬
1件: CHRM3 💬 D08441 💬 Propiverine 1件: 226 💬
54 Gastric acid secretion 💬
1件: CHRM3 💬 D00765 💬 Rocuronium 1件: 296 💬
55 Gastric acid secretion 💬
1件: CHRM3 💬 D00138 💬 Scopolamine 1件:  2  💬
56 Gastric acid secretion 💬
1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
57 Gastric acid secretion 💬
1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
58 Gastric acid secretion 💬
1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
59 Gastric acid secretion 💬
1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
60 Gastric acid secretion 💬
1件: CHRM3 💬 D00787 💬 Trihexyphenidyl 2件:  5 ,  6  💬
61 Gastric acid secretion 💬
1件: CHRM3 💬 D08638 💬 Trihexyphenidyl 2件:  5 ,  6  💬
62 Gastric acid secretion 💬
1件: CHRM3 💬 D00397 💬 Tropicamide 3件:  6 , 13, 19 💬
63 Gastric acid secretion 💬
1件: HRH2 💬 D00295 💬 Cimetidine 2件:  2 , 254 💬
64 Gastric acid secretion 💬
1件: HRH2 💬 D03503 💬 Cimetidine 2件:  2 , 254 💬
65 Gastric acid secretion 💬
1件: HRH2 💬 D00318 💬 Famotidine 7件:  6 , 46, 61, 86, 98, 107, 300 💬
66 Gastric acid secretion 💬
1件: HRH2 💬 D08040 💬 Histamine 1件: 13 💬
67 Gastric acid secretion 💬
1件: HRH2 💬 D00422 💬 Ranitidine 2件: 13, 65 💬
68 Gastric acid secretion 💬
1件: HRH2 💬 D00673 💬 Ranitidine 2件: 13, 65 💬
69 Gastric acid secretion 💬
1件: KCNQ1 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
70 Gastric acid secretion 💬
1件: KCNQ1 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
71 Gastric acid secretion 💬
1件: KCNQ1 💬 D09569 💬 Ezogabine 2件:  2 , 144 💬
72 Gastric acid secretion 💬
1件: SSTR2 💬 D00442 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
73 Gastric acid secretion 💬
1件: SSTR2 💬 D06495 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
74 Gastric acid secretion 💬
1件: SSTR2 💬 D10147 💬 Pasireotide 3件: 67, 74, 75 💬
75 Gastric acid secretion 💬
1件: SSTR2 💬 D07431 💬 Somatostatin 2件: 67, 78 💬