Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D09916 Ivacaftor 1件: 299
2 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D10134 Lumacaftor 1件: 299
3 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11041 Tezacaftor 1件: 299
4 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11423 Deutivacaftor 1件: 299
5 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11507 Elexacaftor 1件: 299
6 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11724 Galicaftor 1件: 299