Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Bile secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin 1件: 299 💬
2 Bile secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin 3件:  8 , 46, 210 💬
3 Bile secretion 💬
1件: CA2 💬 D00218 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
4 Bile secretion 💬
1件: CA2 💬 D01196 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
5 Bile secretion 💬
1件: CA2 💬 D00518 💬 Diclofenamide 1件: 114 💬
6 Bile secretion 💬
1件: CA2 💬 D00653 💬 Dorzolamide 1件: 90 💬
7 Bile secretion 💬
1件: CA2 💬 D07871 💬 Dorzolamide 1件: 90 💬
8 Bile secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
9 Bile secretion 💬
1件: CFTR 💬 D11423 💬 Deutivacaftor 1件: 299 💬
10 Bile secretion 💬
1件: CFTR 💬 D11507 💬 Elexacaftor 1件: 299 💬
11 Bile secretion 💬
1件: CFTR 💬 D11724 💬 Galicaftor 1件: 299 💬
12 Bile secretion 💬
1件: CFTR 💬 D09916 💬 Ivacaftor 1件: 299 💬
13 Bile secretion 💬
1件: CFTR 💬 D10134 💬 Lumacaftor 1件: 299 💬
14 Bile secretion 💬
1件: CFTR 💬 D11041 💬 Tezacaftor 1件: 299 💬
15 Bile secretion 💬
1件: HMGCR 💬 D00887 💬 Atorvastatin 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
16 Bile secretion 💬
1件: HMGCR 💬 D07474 💬 Atorvastatin 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
17 Bile secretion 💬
1件: HMGCR 💬 D00892 💬 Fluvastatin 3件: 79, 218, 222 💬
18 Bile secretion 💬
1件: HMGCR 💬 D07983 💬 Fluvastatin 3件: 79, 218, 222 💬
19 Bile secretion 💬
1件: HMGCR 💬 D00359 💬 Lovastatin 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
20 Bile secretion 💬
1件: HMGCR 💬 D00893 💬 Pravastatin 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
21 Bile secretion 💬
1件: HMGCR 💬 D08410 💬 Pravastatin 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
22 Bile secretion 💬
1件: HMGCR 💬 D01915 💬 Rosuvastatin 11件:  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
23 Bile secretion 💬
1件: HMGCR 💬 D08492 💬 Rosuvastatin 11件:  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
24 Bile secretion 💬
1件: HMGCR 💬 D00434 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
25 Bile secretion 💬
1件: NR1H4 💬 D00163 💬 Chenodeoxycholic acid 4件: 20, 96, 234, 263 💬
26 Bile secretion 💬
1件: NR1H4 💬 D10699 💬 Cholic Acid 4件: 20, 234, 265, 310 💬
27 Bile secretion 💬
1件: NR1H4 💬 D09360 💬 Obeticholic acid 3件: 93, 265, 296 💬
28 Bile secretion 💬
1件: NR1H4 💬 D11548 💬 Tropifexor 1件: 93 💬
29 Bile secretion 💬
1件: NR1H4 💬 D00734 💬 Ursodeoxycholic acid 14件:  6 ,  8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
30 Bile secretion 💬
1件: RXRA 💬 D02754 💬 Acitretin 1件: 37 💬
31 Bile secretion 💬
1件: RXRA 💬 D02815 💬 Alitretinoin 1件: 49 💬
32 Bile secretion 💬
1件: RXRA 💬 D03106 💬 Bexarotene 2件: 13, 75 💬
33 Bile secretion 💬
2件: SLC10A1, SLC10A2 💬 D10951 💬 Maralixibat 3件: 296, 297, 338 💬
34 Bile secretion 💬
1件: SLC10A2 💬 D10796 💬 Elobixibat 1件:  6  💬
35 Bile secretion 💬
1件: SLC10A2 💬 D11716 💬 Odevixibat 3件: 296, 297, 338 💬