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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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97 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2  Adipocytokine signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 3  Adrenergic signaling in cardiomyocytes 
 6 genes, 4 drugs (DrugBank) and 21 diseases shown 
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 1件: SCN5A   D00358   Lidocaine   10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 
 D02086 
 D08127 
 4  Alanine, aspartate and glutamate metabolism 
 4 genes, 1 drug (DrugBank) and 14 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 5  Aldosterone synthesis and secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 6  AMPK signaling pathway 
 2 genes, 2 drugs (DrugBank) and 40 diseases shown 
 1件: ADRA1A   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 7  Antifolate resistance 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 8  Apelin signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 9  Arachidonic acid metabolism 
 2 genes, 1 drug (DrugBank) and 13 diseases shown 
 2件: PTGS1, PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 10  Autophagy - animal 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 11  Autophagy - other 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 12  beta-Alanine metabolism 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: ABAT, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 13  Breast cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 14  Butanoate metabolism 
 4 genes, 1 drug (DrugBank) and 14 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 15  C-type lectin receptor signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 16  Calcium signaling pathway 
 10 genes, 5 drugs (DrugBank) and 32 diseases shown 
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 1件: HRH1   D00300   Diphenhydramine   5件: 49, 51, 70, 86, 256 
 D00669 
 D02419 
 D03285 
 D03360 
 D03854 
 17  cAMP signaling pathway 
 2 genes, 3 drugs (DrugBank) and 19 diseases shown 
 2件: ADRB1, ADRB2   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 18  Cellular senescence 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 19  Central carbon metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 20  cGMP-PKG signaling pathway 
 9 genes, 3 drugs (DrugBank) and 19 diseases shown 
 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 21  Chemical carcinogenesis 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 22  Choline metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 23  Cholinergic synapse 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: ACHE   D00487   Pyridostigmine   4件: 3, 6, 11, 256 
 24  Circadian entrainment 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 25  Colorectal cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 26  Cortisol synthesis and secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 27  Cushing syndrome 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 28  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: ADRB1   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 29  Dopaminergic synapse 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: SCN1A   D00358   Lidocaine   10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 
 D02086 
 D08127 
 30  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 31  Endocrine resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 32  ErbB signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 33  Folate biosynthesis 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 34  GABAergic synapse 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: ABAT, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 35  Galactose metabolism 
 1 gene, 2 drugs (DrugBank) and 1 disease shown 
 1件: GAA   D03207   Alglucosidase alfa   1件: 256 
 D09605   Duvoglustat   1件: 256 
 36  Gap junction 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: ADRB1   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 37  Gastric cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 38  Glioma 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 39  Glycerophospholipid metabolism 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: ACHE   D00487   Pyridostigmine   4件: 3, 6, 11, 256 
 40  GnRH secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 41  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 42  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank) and 42 diseases shown 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 43  Hepatocellular carcinoma 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 44  Herpes simplex virus 1 infection 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 45  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 46  Human cytomegalovirus infection 
 2 genes, 2 drugs (DrugBank) and 41 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 47  Human immunodeficiency virus 1 infection 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 48  Human papillomavirus infection 
 2 genes, 2 drugs (DrugBank) and 41 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 49  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 50  Inflammatory mediator regulation of TRP channels 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: HRH1   D00300   Diphenhydramine   5件: 49, 51, 70, 86, 256 
 D00669 
 D02419 
 D03285 
 D03360 
 D03854 
 51  Insulin resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 52  Insulin signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 53  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 54  Kaposi sarcoma-associated herpesvirus infection 
 2 genes, 2 drugs (DrugBank) and 41 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 55  Leishmaniasis 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 56  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 57  Longevity regulating pathway - multiple species 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 58  Lysosome 
 1 gene, 2 drugs (DrugBank) and 1 disease shown 
 1件: GAA   D03207   Alglucosidase alfa   1件: 256 
 D09605   Duvoglustat   1件: 256 
 59  MAPK signaling pathway 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 60  Metabolic pathways 
 10 genes, 6 drugs (DrugBank) and 48 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: GAA   D03207   Alglucosidase alfa   1件: 256 
 D09605   Duvoglustat   1件: 256 
 2件: PTGS1, PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 1件: UGCG   D05032   Miglustat   3件: 19, 256, 299 
 61  MicroRNAs in cancer 
 2 genes, 2 drugs (DrugBank) and 41 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 62  mTOR signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 63  Neuroactive ligand-receptor interaction 
 10 genes, 4 drugs (DrugBank) and 21 diseases shown 
 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 1件: HRH1   D00300   Diphenhydramine   5件: 49, 51, 70, 86, 256 
 D00669 
 D02419 
 D03285 
 D03360 
 D03854 
 64  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 65  One carbon pool by folate 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 66  Ovarian steroidogenesis 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 67  Oxytocin signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 68  Pancreatic cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 69  Pathways in cancer 
 2 genes, 2 drugs (DrugBank) and 41 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 70  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 71  Phospholipase D signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 72  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 73  Platelet activation 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS1   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 74  Propanoate metabolism 
 1 gene, 1 drug (DrugBank) and 14 diseases shown 
 1件: ABAT   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 75  Prostate cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 76  Proteasome 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PSMB5   D03150   Bortezomib   13件: 11, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 288, 331 
 77  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 78  Regulation of lipolysis in adipocytes 
 5 genes, 4 drugs (DrugBank) and 24 diseases shown 
 3件: ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 2件: PTGS1, PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 79  Renin secretion 
 3 genes, 3 drugs (DrugBank) and 19 diseases shown 
 3件: ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 80  Retrograde endocannabinoid signaling 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 81  Salivary secretion 
 6 genes, 3 drugs (DrugBank) and 19 diseases shown 
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: ADRB2   D07713   Clenbuterol   2件: 1, 256 
 D02147   Salbutamol   13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 82  Serotonergic synapse 
 2 genes, 1 drug (DrugBank) and 13 diseases shown 
 2件: PTGS1, PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 83  Shigellosis 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 84  Small cell lung cancer 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 85  Sphingolipid metabolism 
 1 gene, 1 drug (DrugBank) and 3 diseases shown 
 1件: UGCG   D05032   Miglustat   3件: 19, 256, 299 
 86  Starch and sucrose metabolism 
 1 gene, 2 drugs (DrugBank) and 1 disease shown 
 1件: GAA   D03207   Alglucosidase alfa   1件: 256 
 D09605   Duvoglustat   1件: 256 
 87  Taste transduction 
 3 genes, 1 drug (DrugBank) and 10 diseases shown 
 3件: SCN2A, SCN3A, SCN9A   D00358   Lidocaine   10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 
 D02086 
 D08127 
 88  Taurine and hypotaurine metabolism 
 2 genes, 1 drug (DrugBank) and 14 diseases shown 
 2件: GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 89  Th17 cell differentiation 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 90  Thermogenesis 
 2 genes, 2 drugs (DrugBank) and 40 diseases shown 
 1件: ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 91  Thyroid hormone signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 92  TNF signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 93  Type I diabetes mellitus 
 2 genes, 1 drug (DrugBank) and 14 diseases shown 
 2件: GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 94  Type II diabetes mellitus 
 2 genes, 2 drugs (DrugBank) and 43 diseases shown 
 1件: CACNA1G   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 95  Valine, leucine and isoleucine degradation 
 1 gene, 1 drug (DrugBank) and 14 diseases shown 
 1件: ABAT   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 96  Vascular smooth muscle contraction 
 3 genes, 1 drug (DrugBank) and 9 diseases shown 
 3件: ADRA1A, ADRA1B, ADRA1D   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 97  VEGF signaling pathway 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PTGS2   D00217   Acetaminophen   13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 

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