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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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13 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Calcium signaling pathway 
 2 genes, 1 drug (DrugBank) and 10 diseases shown 
 2件: EDNRA, EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 2  cAMP signaling pathway 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: EDNRA   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 3  cGMP-PKG signaling pathway 
 2 genes, 1 drug (DrugBank) and 10 diseases shown 
 2件: EDNRA, EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 4  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 5  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 6  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 7  Melanogenesis 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 8  Neuroactive ligand-receptor interaction 
 2 genes, 1 drug (DrugBank) and 10 diseases shown 
 2件: EDNRA, EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 9  Pathways in cancer 
 3 genes, 2 drugs (DrugBank) and 17 diseases shown 
 2件: EDNRA, EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 10  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 11  Relaxin signaling pathway 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: EDNRB   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 12  Renin secretion 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: EDNRA   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 
 13  Vascular smooth muscle contraction 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: EDNRA   D01227   Bosentan   10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 
 D07538 

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