Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CSF3R 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03235 Filgrastim 34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
2 EDNRA 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Renin secretion 💬, Pathways in cancer 💬 D01227 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
3 EDNRA 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Renin secretion 💬, Pathways in cancer 💬 D07538 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
4 EDNRB 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Melanogenesis 💬, Relaxin signaling pathway 💬, Pathways in cancer 💬 D01227 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5 EDNRB 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Melanogenesis 💬, Relaxin signaling pathway 💬, Pathways in cancer 💬 D07538 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
6 EPOR 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03231 Erythropoietin 10件: 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
7 SERPINC1 1件: Complement and coagulation cascades 💬 D07510 Heparin 12件: 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
8 PTGIR 3件: Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Platelet activation 💬 D09994 Selexipag 6件: 47, 51, 70, 84, 86, 88