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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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44 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: KIT   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 2  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 3  Axon guidance 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 4  Bladder cancer 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 5  Breast cancer 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: KIT   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 6  Calcium signaling pathway 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 7  Cell cycle 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 8  Central carbon metabolism in cancer 
 2 genes, 1 drug (DrugBank) and 11 diseases shown 
 2件: KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 9  Choline metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 10  Chronic myeloid leukemia 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 11  EGFR tyrosine kinase inhibitor resistance 
 2 genes, 2 drugs (DrugBank) and 14 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 12  Endocytosis 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 13  ErbB signaling pathway 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 14  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 15  Focal adhesion 
 2 genes, 2 drugs (DrugBank) and 14 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 16  Gap junction 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 17  Glioma 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 18  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: KIT   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 19  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 20  Human cytomegalovirus infection 
 2 genes, 2 drugs (DrugBank) and 14 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 21  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 22  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 23  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 24  MAPK signaling pathway 
 3 genes, 2 drugs (DrugBank) and 14 diseases shown 
 2件: KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 25  Melanogenesis 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: KIT   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 26  Melanoma 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 27  MicroRNAs in cancer 
 3 genes, 2 drugs (DrugBank) and 14 diseases shown 
 2件: ABL1, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 28  Neurotrophin signaling pathway 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 29  Pancreatic cancer 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 30  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 31  Pathways in cancer 
 4 genes, 2 drugs (DrugBank) and 14 diseases shown 
 3件: ABL1, KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 32  Phospholipase D signaling pathway 
 2 genes, 1 drug (DrugBank) and 11 diseases shown 
 2件: KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 33  PI3K-Akt signaling pathway 
 3 genes, 2 drugs (DrugBank) and 14 diseases shown 
 2件: KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 34  Prostate cancer 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 35  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 36  Rap1 signaling pathway 
 3 genes, 2 drugs (DrugBank) and 14 diseases shown 
 2件: KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 37  Ras signaling pathway 
 4 genes, 2 drugs (DrugBank) and 14 diseases shown 
 3件: ABL1, KIT, PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 38  Regulation of actin cytoskeleton 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: PDGFRA   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 39  Relaxin signaling pathway 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 40  Renal cell carcinoma 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 41  Rheumatoid arthritis 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 42  Shigellosis 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 43  VEGF signaling pathway 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: VEGFA   D06409   Bevacizumab   9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 
 44  Viral myocarditis 
 1 gene, 1 drug (DrugBank) and 11 diseases shown 
 1件: ABL1   D01441   Imatinib   11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 

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