Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
2 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D06402 Sunitinib 2件: 28, 34
3 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
4 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08552 Sunitinib 2件: 28, 34
5 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08953 Nilotinib 5件: 6, 8, 34, 51, 86
6 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D10481 Nintedanib 5件: 51, 85, 89, 227, 228