Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
3 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
4 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
6 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
7 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
8 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00349 💬 Isradipine 1件:  6  💬
9 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
10 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
11 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
12 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D01908 💬 Nilvadipine 1件: 90 💬
13 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
14 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
15 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
16 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
17 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
18 Amphetamine addiction 💬
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
19 Amphetamine addiction 💬
1件: DDC 💬 D03082 💬 Benserazide 1件:  6  💬
20 Amphetamine addiction 💬
1件: DDC 💬 D00558 💬 Carbidopa 9件:  2 ,  4 ,  6 , 13, 17, 90, 140, 164, 201 💬
21 Amphetamine addiction 💬
1件: DRD1 💬 D02004 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
22 Amphetamine addiction 💬
1件: DRD1 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
23 Amphetamine addiction 💬
1件: DRD1 💬 D09886 💬 Dexpramipexole 1件:  2  💬
24 Amphetamine addiction 💬
1件: DRD1 💬 D00633 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
25 Amphetamine addiction 💬
1件: DRD1 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
26 Amphetamine addiction 💬
1件: DRD1 💬 D01044 💬 Flupentixol 1件: 97 💬
27 Amphetamine addiction 💬
1件: DRD1 💬 D11839 💬 Foslevodopa 1件:  6  💬
28 Amphetamine addiction 💬
1件: DRD1 💬 D00059 💬 Levodopa 8件:  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
29 Amphetamine addiction 💬
1件: DRD1 💬 D00502 💬 Pergolide 1件:  6  💬
30 Amphetamine addiction 💬
1件: DRD1 💬 D08339 💬 Pergolide 1件:  6  💬
31 Amphetamine addiction 💬
1件: DRD1 💬 D11431 💬 Tavapadon 1件:  6  💬
32 Amphetamine addiction 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
33 Amphetamine addiction 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
34 Amphetamine addiction 💬
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
35 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
36 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
37 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
38 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
39 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
40 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
41 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
42 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
43 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
44 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
45 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
46 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
47 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
48 Amphetamine addiction 💬
2件: HDAC1, HDAC2 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
49 Amphetamine addiction 💬
1件: MAOA 💬 D02561 💬 Moclobemide 1件:  6  💬
50 Amphetamine addiction 💬
2件: MAOA, MAOB 💬 D02579 💬 Iproniazid 1件:  6  💬
51 Amphetamine addiction 💬
2件: MAOA, MAOB 💬 D00505 💬 Phenelzine 1件:  6  💬
52 Amphetamine addiction 💬
2件: MAOA, MAOB 💬 D08349 💬 Phenelzine 1件:  6  💬
53 Amphetamine addiction 💬
3件: MAOA, MAOB, SLC6A3 💬 D05458 💬 Phentermine 1件: 97 💬
54 Amphetamine addiction 💬
3件: MAOA, MAOB, SLC6A3 💬 D05459 💬 Phentermine 1件: 97 💬
55 Amphetamine addiction 💬
1件: MAOB 💬 D02562 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
56 Amphetamine addiction 💬
1件: MAOB 💬 D08469 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
57 Amphetamine addiction 💬
1件: MAOB 💬 D10829 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
58 Amphetamine addiction 💬
1件: MAOB 💬 D10158 💬 Safinamide 2件:  6 , 17 💬
59 Amphetamine addiction 💬
1件: MAOB 💬 D00785 💬 Selegiline 1件:  6  💬
60 Amphetamine addiction 💬
1件: MAOB 💬 D03731 💬 Selegiline 1件:  6  💬
61 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
62 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
63 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
64 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
65 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
66 Amphetamine addiction 💬
1件: SLC18A2 💬 D10701 💬 Deutetrabenazine 1件:  8  💬
67 Amphetamine addiction 💬
1件: SLC18A2 💬 D08575 💬 Tetrabenazine 1件:  8  💬
68 Amphetamine addiction 💬
1件: SLC18A2 💬 D10675 💬 Valbenazine 1件:  8  💬
69 Amphetamine addiction 💬
1件: SLC6A3 💬 D03215 💬 Armodafinil 3件:  6 , 13, 84 💬
70 Amphetamine addiction 💬
1件: SLC6A3 💬 D00817 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
71 Amphetamine addiction 💬
1件: SLC6A3 💬 D07591 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
72 Amphetamine addiction 💬
1件: SLC6A3 💬 D07938 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
73 Amphetamine addiction 💬
1件: SLC6A3 💬 D08130 💬 Lisdexamfetamine 1件: 13 💬
74 Amphetamine addiction 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
75 Amphetamine addiction 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬