Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
2 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
3 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00777 Amantadine 4件: 6, 8, 13, 127
4 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
5 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D02780 Acamprosate 2件: 6, 206
6 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
7 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
8 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
9 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07058 Acamprosate 2件: 6, 206
10 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07283 Esketamine 3件: 2, 4, 70
11 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07441 Amantadine 4件: 6, 8, 13, 127
12 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
13 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
14 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D09917 Latrepirdine 1件: 8