Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Cocaine addiction 💬
1件: DDC 💬 D03082 💬 Benserazide 1件:  6  💬
2 Cocaine addiction 💬
1件: DDC 💬 D00558 💬 Carbidopa 9件:  2 ,  4 ,  6 , 13, 17, 90, 140, 164, 201 💬
3 Cocaine addiction 💬
1件: DRD1 💬 D11431 💬 Tavapadon 1件:  6  💬
4 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D02004 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
5 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
6 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D09886 💬 Dexpramipexole 1件:  2  💬
7 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D00633 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
8 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
9 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D01044 💬 Flupentixol 1件: 97 💬
10 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D11839 💬 Foslevodopa 1件:  6  💬
11 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D00059 💬 Levodopa 8件:  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
12 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D00502 💬 Pergolide 1件:  6  💬
13 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D08339 💬 Pergolide 1件:  6  💬
14 Cocaine addiction 💬
1件: DRD2 💬 D01164 💬 Aripiprazole 2件:  6 , 206 💬
15 Cocaine addiction 💬
1件: DRD2 💬 D00780 💬 Bromocriptine 2件:  6 , 74 💬
16 Cocaine addiction 💬
1件: DRD2 💬 D03165 💬 Bromocriptine 2件:  6 , 74 💬
17 Cocaine addiction 💬
1件: DRD2 💬 D00702 💬 Buspirone 3件:  6 , 51, 179 💬
18 Cocaine addiction 💬
1件: DRD2 💬 D07593 💬 Buspirone 3件:  6 , 51, 179 💬
19 Cocaine addiction 💬
1件: DRD2 💬 D00987 💬 Cabergoline 3件:  6 , 74, 75 💬
20 Cocaine addiction 💬
1件: DRD2 💬 D09997 💬 Cariprazine 1件: 21 💬
21 Cocaine addiction 💬
1件: DRD2 💬 D00270 💬 Chlorpromazine 1件: 254 💬
22 Cocaine addiction 💬
1件: DRD2 💬 D00789 💬 Chlorpromazine 1件: 254 💬
23 Cocaine addiction 💬
1件: DRD2 💬 D03274 💬 Chlorpromazine 1件: 254 💬
24 Cocaine addiction 💬
1件: DRD2 💬 D04034 💬 Chlorpromazine 1件: 254 💬
25 Cocaine addiction 💬
1件: DRD2 💬 D01745 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
26 Cocaine addiction 💬
1件: DRD2 💬 D07868 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
27 Cocaine addiction 💬
1件: DRD2 💬 D00136 💬 Haloperidol 1件:  8  💬
28 Cocaine addiction 💬
1件: DRD2 💬 D01898 💬 Haloperidol 1件:  8  💬
29 Cocaine addiction 💬
1件: DRD2 💬 D01462 💬 Lisuride 2件:  6 , 86 💬
30 Cocaine addiction 💬
1件: DRD2 💬 D08132 💬 Lisuride 2件:  6 , 86 💬
31 Cocaine addiction 💬
1件: DRD2 💬 D07309 💬 Melperone 1件:  6  💬
32 Cocaine addiction 💬
1件: DRD2 💬 D00726 💬 Metoclopramide 1件: 51 💬
33 Cocaine addiction 💬
1件: DRD2 💬 D02213 💬 Metoclopramide 1件: 51 💬
34 Cocaine addiction 💬
1件: DRD2 💬 D05008 💬 Metoclopramide 1件: 51 💬
35 Cocaine addiction 💬
1件: DRD2 💬 D00454 💬 Olanzapine 2件:  2 ,  8  💬
36 Cocaine addiction 💬
1件: DRD2 💬 D06623 💬 Olanzapine 2件:  2 ,  8  💬
37 Cocaine addiction 💬
1件: DRD2 💬 D09397 💬 Pardoprunox 1件:  6  💬
38 Cocaine addiction 💬
1件: DRD2 💬 D00560 💬 Pimozide 1件:  2  💬
39 Cocaine addiction 💬
1件: DRD2 💬 D07305 💬 Piribedil 1件:  6  💬
40 Cocaine addiction 💬
1件: DRD2 💬 D00559 💬 Pramipexole 3件:  2 ,  6 , 20 💬
41 Cocaine addiction 💬
1件: DRD2 💬 D05575 💬 Pramipexole 3件:  2 ,  6 , 20 💬
42 Cocaine addiction 💬
1件: DRD2 💬 D09953 💬 Pridopidine 3件:  2 ,  6 ,  8  💬
43 Cocaine addiction 💬
1件: DRD2 💬 D00458 💬 Quetiapine 2件:  6 , 13 💬
44 Cocaine addiction 💬
1件: DRD2 💬 D08456 💬 Quetiapine 2件:  6 , 13 💬
45 Cocaine addiction 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
46 Cocaine addiction 💬
1件: DRD2 💬 D00784 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
47 Cocaine addiction 💬
1件: DRD2 💬 D08489 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
48 Cocaine addiction 💬
1件: DRD2 💬 D05768 💬 Rotigotine 2件:  6 , 127 💬
49 Cocaine addiction 💬
1件: DRD2 💬 D01226 💬 Sulpiride 5件:  2 ,  6 , 17, 46, 70 💬
50 Cocaine addiction 💬
1件: DRD2 💬 D08549 💬 Sulpiride 5件:  2 ,  6 , 17, 46, 70 💬
51 Cocaine addiction 💬
1件: DRD2 💬 D01348 💬 Terguride 2件: 51, 86 💬
52 Cocaine addiction 💬
1件: DRD2 💬 D08590 💬 Tiapride 1件:  8  💬
53 Cocaine addiction 💬
1件: DRD2 💬 D00799 💬 Trifluoperazine 2件: 283, 284 💬
54 Cocaine addiction 💬
1件: DRD2 💬 D01448 💬 Trifluoperazine 2件: 283, 284 💬
55 Cocaine addiction 💬
1件: DRD2 💬 D08636 💬 Trifluoperazine 2件: 283, 284 💬
56 Cocaine addiction 💬
1件: GRIA2 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
57 Cocaine addiction 💬
1件: GRIA2 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
58 Cocaine addiction 💬
1件: GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
59 Cocaine addiction 💬
6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
60 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
61 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
62 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
63 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
64 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
65 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
66 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
67 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
68 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
69 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
70 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
71 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
72 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
73 Cocaine addiction 💬
1件: MAOA 💬 D02561 💬 Moclobemide 1件:  6  💬
74 Cocaine addiction 💬
2件: MAOA, MAOB 💬 D02579 💬 Iproniazid 1件:  6  💬
75 Cocaine addiction 💬
2件: MAOA, MAOB 💬 D00505 💬 Phenelzine 1件:  6  💬
76 Cocaine addiction 💬
2件: MAOA, MAOB 💬 D08349 💬 Phenelzine 1件:  6  💬
77 Cocaine addiction 💬
3件: MAOA, MAOB, SLC6A3 💬 D05458 💬 Phentermine 1件: 97 💬
78 Cocaine addiction 💬
3件: MAOA, MAOB, SLC6A3 💬 D05459 💬 Phentermine 1件: 97 💬
79 Cocaine addiction 💬
1件: MAOB 💬 D02562 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
80 Cocaine addiction 💬
1件: MAOB 💬 D08469 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
81 Cocaine addiction 💬
1件: MAOB 💬 D10829 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
82 Cocaine addiction 💬
1件: MAOB 💬 D10158 💬 Safinamide 2件:  6 , 17 💬
83 Cocaine addiction 💬
1件: MAOB 💬 D00785 💬 Selegiline 1件:  6  💬
84 Cocaine addiction 💬
1件: MAOB 💬 D03731 💬 Selegiline 1件:  6  💬
85 Cocaine addiction 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
86 Cocaine addiction 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
87 Cocaine addiction 💬
1件: SLC18A2 💬 D10701 💬 Deutetrabenazine 1件:  8  💬
88 Cocaine addiction 💬
1件: SLC18A2 💬 D08575 💬 Tetrabenazine 1件:  8  💬
89 Cocaine addiction 💬
1件: SLC18A2 💬 D10675 💬 Valbenazine 1件:  8  💬
90 Cocaine addiction 💬
1件: SLC6A3 💬 D03215 💬 Armodafinil 3件:  6 , 13, 84 💬
91 Cocaine addiction 💬
1件: SLC6A3 💬 D00817 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
92 Cocaine addiction 💬
1件: SLC6A3 💬 D07591 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
93 Cocaine addiction 💬
1件: SLC6A3 💬 D07938 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
94 Cocaine addiction 💬
1件: SLC6A3 💬 D08130 💬 Lisdexamfetamine 1件: 13 💬
95 Cocaine addiction 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
96 Cocaine addiction 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬