Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 ErbB signaling pathway 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 ErbB signaling pathway 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
3 ErbB signaling pathway 💬
 2件: ABL1, SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
4 ErbB signaling pathway 💬
 2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
5 ErbB signaling pathway 💬
 2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
6 ErbB signaling pathway 💬
 2件: ABL1, SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
7 ErbB signaling pathway 💬
 1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
8 ErbB signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
9 ErbB signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬
10 ErbB signaling pathway 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬
11 ErbB signaling pathway 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
12 ErbB signaling pathway 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
13 ErbB signaling pathway 💬
 2件: EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
14 ErbB signaling pathway 💬
 2件: EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
15 ErbB signaling pathway 💬
 3件: EGFR, ERBB2, ERBB4 💬 Neratinib 💬 Neratinib 1件: 34 💬
16 ErbB signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
17 ErbB signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
18 ErbB signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
19 ErbB signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
20 ErbB signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
21 ErbB signaling pathway 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
22 ErbB signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
23 ErbB signaling pathway 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬
24 ErbB signaling pathway 💬
 1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
25 ErbB signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
26 ErbB signaling pathway 💬
 1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
27 ErbB signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬